{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T07:45:34Z","timestamp":1768463134498,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,30]],"date-time":"2005-12-30T00:00:00Z","timestamp":1135900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chirality"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A general method was found for the resolution of the racemic 1\u2010phenyl\u20101\u2010propanol (<jats:bold>1<\/jats:bold>) and 1\u2010phenyl\u20102\u2010propanol (<jats:bold>2<\/jats:bold>) with various resolving agents. Monoesters of the alcohols were prepared, which were then reacted with different chiral bases. Successful optical resolutions were achieved only with the maleic acid monoesters (<jats:bold>3<\/jats:bold> and <jats:bold>6<\/jats:bold>). Alcohol <jats:bold>1<\/jats:bold> has been resolved to &gt;99% enantiomeric excess by diastereoisomeric salt formation via its maleic acid monoester (<jats:bold>3<\/jats:bold>) using cinchonidine (<jats:bold>9<\/jats:bold>) as resolving agent. Alcohol <jats:bold>2<\/jats:bold> has been obtained in 98% enantiomeric excess by diastereoisomeric salt formation via its the maleic acid monoester (<jats:bold>6<\/jats:bold>) using (+)\u2010dehydroabietylamine (<jats:bold>11<\/jats:bold>) as resolving agent. \u00a9 2005 Wiley\u2010Liss, Inc. <jats:italic>Chirality 18:116\u2013120, 2006.<\/jats:italic><\/jats:p>","DOI":"10.1002\/chir.20226","type":"journal-article","created":{"date-parts":[[2005,12,30]],"date-time":"2005-12-30T12:47:26Z","timestamp":1135946846000},"page":"116-120","source":"Crossref","is-referenced-by-count":8,"title":["Enantioseparation of secondary alcohols by diastereoisomeric salt formation"],"prefix":"10.1002","volume":"18","author":[{"given":"Violetta","family":"Kiss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Egri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"B\u00e1lint","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elem\u00e9r","family":"Fogassy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,30]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1039\/c39880001459"},{"key":"e_1_2_1_3_2","first-page":"1978","volume-title":"Optical resolution procedures for chemical compounds, Vol. 1\u20133","author":"Newmann P"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/cber.19741070533"},{"key":"e_1_2_1_4_3","doi-asserted-by":"publisher","DOI":"10.1002\/cber.19801130506"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.198405701"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)87306-3"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1271\/bbb1961.44.863"},{"key":"e_1_2_1_8_2","volume-title":"Enantiomers, racemates and resolution","author":"Jacques J","year":"1981"},{"key":"e_1_2_1_9_2","first-page":"1","article-title":"Chiral synthons by ester hydrolysis catalyzed by pig liver esterase","volume":"37","author":"Ohno M","year":"1989","journal-title":"Org React"},{"key":"e_1_2_1_9_3","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-97423-6"},{"key":"e_1_2_1_9_4","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-035941-0.50005-7"},{"key":"e_1_2_1_9_5","doi-asserted-by":"publisher","DOI":"10.1002\/9783527619429"},{"key":"e_1_2_1_9_6","doi-asserted-by":"publisher","DOI":"10.1021\/cr00013a016"},{"key":"e_1_2_1_9_7","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(95)01021-1"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo010529u"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1039\/p19940001253"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0957-4166(00)80122-6"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4039(96)01658-9"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja00016a032"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0957-4166(96)00429-6"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0957-4166(96)00121-8"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1039\/ct9119900045"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1039\/ct9140501115"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1039\/jr9350001072"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo01281a037"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1039\/jr9560002987"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja01032a035"}],"container-title":["Chirality"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fchir.20226","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/chir.20226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T15:45:15Z","timestamp":1700063115000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/chir.20226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,30]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1002\/chir.20226"],"URL":"https:\/\/doi.org\/10.1002\/chir.20226","archive":["Portico"],"relation":{},"ISSN":["0899-0042","1520-636X"],"issn-type":[{"value":"0899-0042","type":"print"},{"value":"1520-636X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12,30]]}}}