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Often, when a new selector is developed, the versatility of substrate scope is investigated. From an industrial point of view, the problem is typically approached the other way around, and for a target racemate, a selector needs to be found in order to accomplish the desired enantioseparation. This study presents such a screening approach for the separation of the enantiomers of <jats:sc>dl<\/jats:sc>\u2010\u03b1\u2010methyl phenylglycine amide (<jats:sc>dl<\/jats:sc>\u2010\u03b1\u2010MPGA), a model amide racemate with high industrial relevance. Chiral selectors that were reported for other classes of racemates were investigated, i.e.,\u2009several macrocyclic selectors and Pd\u2010BINAP complexes. It appeared very challenging to obtain both high extraction yields and good enantioselectivity for most selectors, but Pd\u2010BINAP\u2010based selectors performed well, with enantioselectivities up to 7.4 with an extraction yield of the desired enantiomer of 95.8%. These high enantioselectivities were obtained using dichloromethane as solvent. Using less volatile chlorobenzene or 1\u2010chloropentane, reasonable selectivities of up to 1.7 were measured, making these the best alternative solvents for dichloromethane. <jats:italic>Chirality 27:123\u2013130, 2015<\/jats:italic>. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/chir.22400","type":"journal-article","created":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T10:28:20Z","timestamp":1413455300000},"page":"123-130","source":"Crossref","is-referenced-by-count":14,"title":["Selector Screening for Enantioseparation of <scp>dl<\/scp>\u2010\u03b1\u2010Methyl Phenylglycine Amide by Liquid\u2013Liquid Extraction"],"prefix":"10.1002","volume":"27","author":[{"given":"Boelo","family":"Schuur","sequence":"first","affiliation":[{"name":"University of Twente Faculty of Science and Technology, Sustainable Process Technology Group  Enschede The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Blahu\u0161iak","sequence":"additional","affiliation":[{"name":"University of Twente Faculty of Science and Technology, Sustainable Process Technology Group  Enschede The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caecilia R.","family":"Vitasari","sequence":"additional","affiliation":[{"name":"Institute for Sustainable Process Technology  Amersfoort The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Grambli\u010dka","sequence":"additional","affiliation":[{"name":"University of Twente Faculty of Science and Technology, Sustainable Process Technology Group  Enschede The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 B.","family":"De Haan","sequence":"additional","affiliation":[{"name":"Delft University of Technology (Biobased) Process Technology, Transport Phenomena, Department of Chemical Engineering  Delft The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ton J.","family":"Visser","sequence":"additional","affiliation":[{"name":"Syncom B.V.  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