{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T23:09:54Z","timestamp":1788390594878,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,3,27]],"date-time":"2009-03-27T00:00:00Z","timestamp":1238112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Methamphetamine is currently the most widespread illegal stimulant abused in the United States. No previous reports comparing echocardiographic findings of cardiomyopathy with and without a history of methamphetamine abuse are available.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a single institution retrospective review of medical records and analyses of echocardiographic findings in patients \u2264 45 years of age hospitalized between 2001 and 2004 who were discharged with a diagnosis of cardiomyopathy or heart failure. After exclusion of patients with coronary artery disease or severe cardiac valvular disease, the remaining patients were divided into 2 groups based on their abuse or non abuse of methamphetamine, as determined by the documented history in the medical records or urine toxicology testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among a total of 59 patients, 28 (47%) had a history of methamphetamine abuse or positive urine toxicology. Both methamphetamine abusers and non\u2010abusers were predominately male (64.3% vs 64.5%, <jats:italic>P<\/jats:italic> = .99), and had a high prevalence of obesity (55.6% vs 73.3%, <jats:italic>P<\/jats:italic> = .16). Bivariate analysis revealed significant differences between the methamphetamine abusers and non\u2010abusers in left atrium volume (119.7 \u00b1 55.4 ml vs 85.8 \u00b1 33.5 ml, <jats:italic>P<\/jats:italic> = .008), left ventricular end\u2010diastolic volume (201.9 \u00b1 71.4 ml vs 156.6 \u00b1 63.1 ml, <jats:italic>P<\/jats:italic> = .01), left ventricular end\u2010systolic volume (136.0 \u00b1 53.7 ml vs 92.3 \u00b1 55.8 ml, <jats:italic>P<\/jats:italic> = .004), right ventricular dimension (26.3 \u00b1 6.0 mm vs 21.3 \u00b1 6.0 mm, <jats:italic>P<\/jats:italic> = .007), and quantified left ventricular ejection fraction (32.9% \u00b1 11.3% vs 44.6% \u00b1 17.8%, <jats:italic>P<\/jats:italic> = .004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found a high prevalence of methamphetamine abuse in our study population. Methamphetamine abusers had echocardiographic findings of more severe dilated cardiomyopathy compared with non\u2010abusers. Copyright \u00a9 2009 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.20367","type":"journal-article","created":{"date-parts":[[2009,3,30]],"date-time":"2009-03-30T13:15:05Z","timestamp":1238418905000},"source":"Crossref","is-referenced-by-count":69,"title":["A Comparison of Echocardiographic Findings in Young Adults With Cardiomyopathy: With and Without a History of Methamphetamine Abuse"],"prefix":"10.1002","volume":"32","author":[{"given":"Hiroki","family":"Ito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khung\u2010Keong","family":"Yeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mevan","family":"Wijetunga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd B.","family":"Seto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Tay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irwin J.","family":"Schatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,27]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Research Report Series: Methamphetamine Abuse and Addiction","author":"National Institute of Drug Abuse"},{"key":"e_1_2_1_3_2","unstructured":"U.S. Drug Enforcement Administration. Methamphetamine. Available at:http:\/\/www.usdoj.gov\/dea\/concern\/meth.html. Acce\u2010 ssed February 16 2007."},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.4065\/81.1.77"},{"key":"e_1_2_1_5_2","unstructured":"Substance Abuse and Mental Health Services Administration. Results from the 2004 National Survey on Drug Use and Health: National Findings September 2005."},{"key":"e_1_2_1_6_2","first-page":"214","article-title":"Methamphetamine and the expanding complications of amphetamines","volume":"170","author":"Albertson T","year":"1999","journal-title":"West J Med."},{"key":"e_1_2_1_7_2","first-page":"449","article-title":"Smokable methamphetamine (\u201cIce\u201d): an old drug in a different form","volume":"51","author":"Beebe D","year":"1995","journal-title":"Am Family Physician."},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1991.03460090100040"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-120026521"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.01.024"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/j.echo.2005.10.005","article-title":"Recommendations for Chamber Quantification: A report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology","volume":"18","author":"Members of the Chamber Quantification Writing Group","year":"2005","journal-title":"J Am Soc Echocardiogr."},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02305-7"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)02290-1"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00780-7"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960121211"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0379-0738(95)01765-B"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000433-199606000-00014"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.fjc.0000211796.45281.46"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1520\/JFS16085J"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1520\/JFS14464J"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90771-X"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.20367","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.20367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T02:05:59Z","timestamp":1699927559000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.20367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,27]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["10.1002\/clc.20367"],"URL":"https:\/\/doi.org\/10.1002\/clc.20367","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,27]]}}}