{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:22:13Z","timestamp":1761675733240},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,2,16]],"date-time":"2010-02-16T00:00:00Z","timestamp":1266278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Current criteria for rate control in atrial fibrillation (AF) treatment are empirical and based on a small amount of scientific data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>This study was designed to analyze the influence of heart rate (HR, measured by the 6\u2010minute walk test [6MWT] and 24\u2010hour Holter monitoring) on quality of life (QoL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 89 male patients with chronic atrial fibrillation (AF) and resting HR &lt; 90 bpm were included. QoL (assessed by the Short Form\u201036 Health Survey [SF\u201036] questionnaire) was compared among 3 groups of patients classified by HR testing results: group 1 had HR \u2264 110 bpm on 6MWT and \u2264 80 bpm on Holter monitor; group 2 had HR in the target area by 1 but not both tests; and group 3 had HR &gt; 110 bpm on 6MWT and &gt; 80 bpm on Holter monitor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were significant differences among the 3 groups in physical and mental component summary scores (285.9 \u00b1 73.9; 276.6 \u00b1 80.8; 230.3 \u00b1 91.0, <jats:italic>P<\/jats:italic> = .035; and 319.8 \u00b1 70.2; 294.7 \u00b1 76.0; 255.0 \u00b1 107.1, <jats:italic>P<\/jats:italic> = .026, respectively).<\/jats:p><jats:p>When the methods were analyzed separately, there was a significant difference on QoL in physical and mental summary scores in patients with maximal HR \u2264 110 bpm on 6MWT in comparison with HR &gt; 110 bpm (<jats:italic>P<\/jats:italic> = .04 and <jats:italic>P<\/jats:italic> = .01, respectively) and in the physical summary score in patients with average HR \u2264 80 bpm on Holter monitor in comparison with HR &gt; 80 bpm (<jats:italic>P<\/jats:italic> = .02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Holter monitoring and 6MWT should be performed as complementary methods to better predict QoL. Copyright \u00a9 2010 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.20528","type":"journal-article","created":{"date-parts":[[2010,2,16]],"date-time":"2010-02-16T22:55:06Z","timestamp":1266360906000},"source":"Crossref","is-referenced-by-count":9,"title":["Influence of Heart Rate on Quality of Life in Patients With Chronic Atrial Fibrillation"],"prefix":"10.1002","volume":"33","author":[{"given":"Jefferson","family":"Jaber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Cirenza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Jaber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Amaral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Marconi","family":"Almeida de Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Japy A.","family":"Oliveira Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo A. 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