{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:52:41Z","timestamp":1762865561474},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2009,9,9]],"date-time":"2009-09-09T00:00:00Z","timestamp":1252454400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Point\u2010of\u2010care (POC) testing may expedite the care of emergency department (ED) patients suspected of having acute coronary syndromes (ACS). We evaluated the use patterns of cardiac bedside markers or POC testing for troponin in patients with non\u2010ST\u2010segment elevation (NSTE) ACS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>NSTE ACS data were collected from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology\/American Heart Association (ACC\/AHA) Guidelines (CRUSADE) registry. We compared hospital and patient characteristics, in\u2010hospital events, and process\u2010of\u2010care variables between hospitals to those that did not use POC testing in \u2265 50% of enrolled patients. We examined characteristics, in\u2010hospital events, and process\u2010of\u2010care differences between patients with negative vs positive troponin POC testing results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 568 hospitals, 74 (16,276 patients) had high POC usage compared with 197 hospitals (50 782 patients) with no troponin POC usage. From the high POC usage hospitals, 12 604 patients had recorded troponin POC test results. Hospitals with high POC usage had a shorter ED length of stay and were less likely to administer aspirin, \u03b2\u2010blockers, and heparin during the first 24 hours of care. Patients with positive troponin POC results were more often older, minority, female, Medicare\u2010insured, diabetic, and renally impaired. They had fewer electrocardiograms within 10 minutes but were more likely to get aspirin, \u03b2\u2010blockers, glycoprotein IIb\/IIIa inhibitors, and heparin within 24 hours of arrival. They also had longer ED lengths of stay, received fewer in\u2010hospital and interventional procedures, and had more adverse clinical events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Differences existed in how hospitals used POC testing and the care given based on those results. Positive POC results are associated with expedited and higher use of anti\u2010ischemic therapies. Copyright \u00a9 2009 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.20626","type":"journal-article","created":{"date-parts":[[2009,9,9]],"date-time":"2009-09-09T21:07:27Z","timestamp":1252530447000},"page":"498-505","source":"Crossref","is-referenced-by-count":13,"title":["The Usage Patterns of Cardiac Bedside Markers Employing Point\u2010of\u2010Care Testing for Troponin in Non\u2010ST\u2010Segment Elevation Acute Coronary Syndrome: Results from CRUSADE"],"prefix":"10.1002","volume":"32","author":[{"given":"Kevin M.","family":"Takakuwa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang\u2010Shu","family":"Ou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric D.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Charles V.","family":"Pollack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. 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