{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T18:21:37Z","timestamp":1705429297120},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T00:00:00Z","timestamp":1303862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>Simultaneous drug\u2010eluting stent (DES) and bare\u2010metal stent (BMS) implantation is occasionally employed in clinical practice, but its long\u2010term clinical and angiographic outcome is not clear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis:<\/jats:title><jats:p>We aimed to describe the long\u2010term clinical outcome and the findings of clinically indicated coronary angiography in patients subjected to simultaneous DES and BMS implantation (\u201chybrid stenting\u201d).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>We identified 236 patients (mean age 62.9 \u00b1 11.4 years, 76.7% men) who had undergone percutaneous coronary intervention with at least 1 DES and 1 BMS. At a median follow\u2010up of 42 months (range, 6\u201389 months) available in 222 patients, 13 (5.9%) patients died from cardiac causes, 13 (5.9%) experienced nonfatal acute myocardial infarction, and 24 (10.8%) experienced unstable angina. Clinically indicated repeat coronary angiography was performed in 64 patients (28.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Thirty\u2010one patients (14%) had target lesion revascularization (TLR). The DES demonstrated lower TLR rates (15.9% vs 36.9%, <jats:italic>P<\/jats:italic> = 0.002) and lower late loss (0.44 \u00b1 0.5 mm vs 0.68 \u00b1 0.7 mm, <jats:italic>P<\/jats:italic> = 0.009) compared with BMS. Use of DES was independently associated with lower risk for binary restenosis (hazard ratio [HR]: 0.41, 95% confidence interval [CI]: 0.19\u20130.89, <jats:italic>P<\/jats:italic> = 0.03) and TLR (HR: 0.26, 95% CI: 0.12\u20130.54, <jats:italic>P&lt;<\/jats:italic>0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Although a hybrid stenting strategy demonstrates a reasonable long\u2010term prognosis even in high\u2010risk patients, DES have a better angiographic outcome compared with BMS under the influence of common patient\u2010related restenosis risk factors. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p><jats:p>The authors have no funding, financial relationships, or conflicts of interest to disclose.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.20878","type":"journal-article","created":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T19:04:28Z","timestamp":1303931068000},"page":"317-321","source":"Crossref","is-referenced-by-count":2,"title":["Simultaneous Drug\u2010Eluting and Bare\u2010Metal Stent Implantation: Long\u2010Term Clinical Outcome and Findings of Clinically Indicated Coronary Angiography"],"prefix":"10.1002","volume":"34","author":[{"given":"Dimitrios","family":"Alexopoulos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioanna","family":"Xanthopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasileios","family":"Karantalis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia","family":"Mitropoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anastasia","family":"Damelou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Periklis","family":"Davlouros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,4,27]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.01.049"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.781377"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20431"},{"key":"e_1_2_6_5_2","first-page":"99","article-title":"Clinical outcomes after multilesion percutaneous coronary intervention: comparison between exclusive and selective use of drug\u2010eluting stents","volume":"20","author":"Bertrand O","year":"2008","journal-title":"J Invasive Cardiol."},{"key":"e_1_2_6_6_2","first-page":"1281","article-title":"Outcome of percutaneous hybrid coronary revascularization: bare metal stents jeopardize the benefit of sirolomus\u2010eluting stents in the real world","volume":"21","author":"Fineschi M","year":"2005","journal-title":"Can J Cardiol."},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.78.2.486"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067722"},{"key":"e_1_2_6_9_2","first-page":"145","article-title":"Treatment of multilesion coronary artery disease with simultaneous drug\u2010eluting and bare\u2010metal stent implantation: clinical follow up and angiographic mid\u2010term results","volume":"21","author":"Mirabella F","year":"2009","journal-title":"J Invasive Cardiol."}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.20878","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.20878","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T21:30:06Z","timestamp":1697491806000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.20878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,27]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1002\/clc.20878"],"URL":"https:\/\/doi.org\/10.1002\/clc.20878","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,27]]}}}