{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:00:38Z","timestamp":1780498838052,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T00:00:00Z","timestamp":1303862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>The treatment of unprotected left main coronary artery (uLMCA) bifurcation lesions remains challenging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis:<\/jats:title><jats:p>We hypothesized that the type of drug\u2010eluting stent would correlate with clinical outcomes for the treatment of uLMCA bifurcation lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>One hundred fifteen patients who underwent stent implantation using a provisional T\u2010stenting technique with sirolimus\u2010eluting stents (SES) or paclitaxel\u2010eluting stents (PES) for uLMCA bifurcation lesions were enrolled. A major adverse cardiac event (MACE) was defined as a composite of cardiac death, myocardial infarction, or target lesion revascularization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Ninety\u2010four patients were treated with SES and 21 patients with PES. Baseline characteristics were similar between the 2 groups. Angiographic follow\u2010up was performed in 99 (86%) patients. Late loss in the LMCA to the left anterior descending coronary artery was significantly lower in the SES group than in the PES group (0.28 \u00b1 0.54 mm vs 1.03 \u00b1 0.45 mm, <jats:italic>P&lt;<\/jats:italic>0.001). One case of stent thrombosis occurred in the SES group. During follow\u2010up with a median of 712 days, the SES group had a lower MACE compared with the PES group (10.6% vs 28.6%, <jats:italic>P<\/jats:italic> = 0.032). Cox proportional hazards models including age, sex, diabetes, acute coronary syndrome, true bifurcation, stenting strategy, and type of drug\u2010eluting stent used (SES vs PES) demonstrated that stent type was the only predictor of MACE (hazard ratio of PES vs SES: 3.88, 95% confidence interval: 1.29\u201311.67, <jats:italic>P<\/jats:italic> = 0.016).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>According to the results of the present study, SES may be associated with more favorable outcomes than PES for stenting of uLMCA bifurcation, which should be further studied by larger trials. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p><jats:p>The authors have no funding, financial relationships, or conflicts of interest to disclose.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.20887","type":"journal-article","created":{"date-parts":[[2011,4,27]],"date-time":"2011-04-27T19:02:30Z","timestamp":1303930950000},"page":"378-383","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010Term Outcomes of Sirolimus\u2010Eluting Stents vs Paclitaxel\u2010Eluting Stents in Unprotected Left Main Coronary Artery Bifurcation Lesions"],"prefix":"10.1002","volume":"34","author":[{"given":"Pil Sang","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Ryeol","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young 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Euy","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeon\u2010Cheol","family":"Gwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,4,27]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.04.055"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.039"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp223"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2006.10.017"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21194"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1157\/13084649"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.685313"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.8.895"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.4.409"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.2.165"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.062"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.06.019"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67221-2"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.01.035"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.071"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035071"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000086926.62288.A6"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.11.063"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.666396"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.06.047"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.10.015"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi138"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.692178"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801441"}],"container-title":["Clinical 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