{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:59:58Z","timestamp":1762505998848},"reference-count":43,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,11,2]],"date-time":"2012-11-02T00:00:00Z","timestamp":1351814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background:<\/jats:title><jats:p>The purpose of this study was to examine the influence of atrial fibrillation (AF) on the immediate and long\u2010term outcome of patients undergoing balloon mitral valvotomy (BMV).<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis:<\/jats:title><jats:p>Patients with atrial fibrillation fair poorly after balloon mitral valvotomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>There were a total of 818 consecutive patients who underwent elective BMV in this institute from 1997 to 2003, with either double\u2010lumen or triple\u2010lumen BMV catheters included in the study. Of them, 95 were with AF. The clinical, echocardiographic, and hemodynamic data of these patients were compared with those of 723 patients in normal sinus rhythm (NSR). Immediate procedural results and long\u2010term events were compared between the 2 study groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Patients with AF were older (39.9 \u00b1 9.9 years vs 29.4 \u00b1 10.1, <jats:italic>P &lt;<\/jats:italic> 0.001) and presented more frequently with New York Heart Association (NYHA) class III\u2010IV (53.7% vs 32.9%, <jats:italic>P &lt;<\/jats:italic> 0.001), echocardiographic score &gt;8 (47.4% vs 24.9%, <jats:italic>P &lt;<\/jats:italic> 0.001), and with history of previous surgical commissurotomy (33.7% vs 11.5%, <jats:italic>P &lt;<\/jats:italic> 0.001). In patients with AF, BMV resulted in inferior immediate and long\u2010term outcomes, as reflected in a lesser post\u2010BMV mitral valve area (1.3 \u00b1 0.4 vs 1.6 \u00b1 0.4 cm<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#bib2\">2<\/jats:ext-link>, <jats:italic>P<\/jats:italic> = 0.032) and higher event rate on follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Patients with AF were older, sicker, and had advanced rheumatic mitral valve disease. They had a higher incidence of stroke, new onset heart failure, and need for reinterventions on long\u2010term follow\u2010up. These patients need intense and more frequent follow\u2010up. <jats:italic>Clin. Cardiol.<\/jats:italic> 2011 DOI: 10.1002\/clc.22068<\/jats:p><jats:p>The authors have no funding, financial relationships, or conflicts of interest to disclose.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22068","type":"journal-article","created":{"date-parts":[[2012,11,2]],"date-time":"2012-11-02T18:21:53Z","timestamp":1351880513000},"source":"Crossref","is-referenced-by-count":11,"title":["Immediate and Long\u2010term Results Following Balloon Mitral Valvotomy in Patients With Atrial Fibrillation"],"prefix":"10.1002","volume":"35","author":[{"given":"Krishna Kumar","family":"Mohanan Nair","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harikrishnan Sivadasan","family":"Pillai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anees","family":"Thajudeen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavassery 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