{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T08:18:27Z","timestamp":1789373907581,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T00:00:00Z","timestamp":1363219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Accumulating evidence has demonstrated that overweight and obesity, expressed as high body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>), are associated with the development of atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) and quality of life (<jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>) in <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> patients. However, the role of high <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> as a risk factor for prognosis and <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> patients undergoing ablation remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>We hypothesized that elevated <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> was correlated with <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence and <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> after an ablative procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a comprehensive search of <jats:styled-content style=\"fixed-case\">PubMed<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">EMBASE<\/jats:styled-content>, and the Cochrane Library. Studies were included if they investigated the association of <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence and <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> after ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 151 articles identified, 12 studies that enrolled 3286 individuals met the inclusion criteria. Overall, compared with normal\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> patients, <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence occured more frequently in high\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> patients after ablation (odds ratio: 1.32, 95% confidence interval: 1.17\u20101.5, <jats:italic>P<\/jats:italic> &lt; 0.001). However, the pooled esimate of odds ratio adjusted for multiple confounders did not reach significance. The summary weighted mean difference of <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> between patients with and without recurrence was 0.43 (95% confidence interval: 0.05\u20100.81, <jats:italic>P<\/jats:italic> = 0.027). In addition, <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> scores were significantly lower in high\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> than in normal\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> patients before the ablative procedure, whereas the gap of <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> between normal\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and high\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> groups was decreased at follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Results of this meta\u2010analysis suggest 2 points, namely that the tight association between overweight\/obesity and <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence after ablation may be partly due to other concomitant conditions, and that impaired <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> in high\u2010<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> groups is significantly improved after ablation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22108","type":"journal-article","created":{"date-parts":[[2013,3,15]],"date-time":"2013-03-15T03:53:05Z","timestamp":1363319585000},"page":"269-275","source":"Crossref","is-referenced-by-count":34,"title":["Influence of Body Mass Index on Recurrence and Quality of Life in Atrial Fibrillation Patients After Catheter Ablation: A Meta\u2010Analysis and Systematic Review"],"prefix":"10.1002","volume":"36","author":[{"given":"Jianhui","family":"Zhuang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Shanghai Tenth People's Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shanghai Tenth People's Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shanghai Tenth People's Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhui","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shanghai Tenth People's Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawei","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shanghai Tenth People's Hospital Tongji University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000216787.85457.f3"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.1.76"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020245"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.20.2471"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.10.004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03510350050036"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.6.581"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.856633"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.824789"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.772582"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050955"},{"key":"e_1_2_7_13_1","unstructured":"CaiL YinY LingZ et al. 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