{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T13:35:19Z","timestamp":1765805719182},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,28]],"date-time":"2013-03-28T00:00:00Z","timestamp":1364428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Three\u2010quarters of rehospitalizations ($44 billion yearly estimated cost) may be avoidable. A\u00a0screening tool for the detection of potential readmission may facilitate more efficient case management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>An elevated red blood cell distribution width (<jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content>) is an independent predictor of hospital readmission in patients with unstable angina (<jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content>) or non\u2013<jats:styled-content style=\"fixed-case\">ST<\/jats:styled-content>\u2010elevation myocardial infarction (<jats:styled-content style=\"fixed-case\">NSTEMI<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study is a retrospective observational cohort analysis of adults admitted in 2007 with <jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">NSTEMI<\/jats:styled-content>. Data were gathered by review of inpatient medical records. The rate of 30\u2010day nonelective readmission and time to nonelective readmission were recorded until November 1, 2011, and compared by <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content> group using the 95th percentile (16.3%) as a cutoff.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median follow\u2010up time of the 503 subjects (average age, 65 \u00b1 13 years; 56% male) was 3.8 years (interquartile range: 0.3\u20134.3 years). Those readmitted within 30 days were older, had more comorbidities and higher <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content> and creatinine levels, and were more likely to have had an intervention. At 3.8 years of follow\u2010up, subjects with high <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content> (&gt;16.3%) were more likely to be readmitted compared to those with normal <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content> (\u226416.3%) (72.28% vs 59.95%, P\u2009=\u20090.003). In multivariable analyses, high <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content> was a statistically significant predictor of readmission in general (hazard ratio: 1.35 (95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]:1.02\u20101.79), P\u2009=\u20090.033) but not of 30\u2010day rehospitalization (odds ratio: 1.34 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.78\u20102.31), P\u2009=\u20090.292). Its area under the receiver operating characteristic curve was 0.54 (sensitivity 23% and specificity 85%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>An elevated <jats:styled-content style=\"fixed-case\">RDW<\/jats:styled-content> is an independent predictor of hospital readmission in patients with <jats:styled-content style=\"fixed-case\">UA<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">NSTEMI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22116","type":"journal-article","created":{"date-parts":[[2013,3,28]],"date-time":"2013-03-28T16:14:37Z","timestamp":1364487277000},"page":"293-299","source":"Crossref","is-referenced-by-count":21,"title":["Red Blood Cell Distribution Width Is a Predictor of Readmission in Cardiac Patients"],"prefix":"10.1002","volume":"36","author":[{"given":"Georges","family":"Ephrem","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Disease Hofstra\u2013North Shore\u2013LIJ Health System  Manhasset New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa0803563"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199905000-00008"},{"key":"e_1_2_7_4_1","unstructured":"HackbarthG ChernewM ArmstrongS et al.A path to bundled payment around a rehospitalization. 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