{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T03:11:47Z","timestamp":1775099507964,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,6,30]],"date-time":"2014-06-30T00:00:00Z","timestamp":1404086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Kaiser Permanente Community Benefit Grant"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Inadequate recruitment of women and an exclusion of patients with end\u2010stage renal disease (ESRD<\/jats:styled-content>) in coronary revascularization trials have led to knowledge gaps of gender\u2010based outcomes.<\/jats:p><\/jats:sec>Hypothesis<\/jats:title>Women have equivalent cardiovascular outcomes when compared to men.<\/jats:p><\/jats:sec>Methods<\/jats:title>We conducted a retrospective observational study utilizing Kaiser Permanente Northern California (KPNC<\/jats:styled-content>) databases and identified 1015 adults with ESRD<\/jats:styled-content> who underwent coronary revascularization between 1996 and 2008. We ascertained baseline characteristics, primary (mortality at 5 years) and secondary (myocardial infarction [MI<\/jats:styled-content>] and repeat revascularization) outcomes from KPNC<\/jats:styled-content> databases, state death certificates, and Social Security Administration files. A multivariable logistic regression was used to determine the association of gender to the prespecified outcomes.<\/jats:p><\/jats:sec>Results<\/jats:title>Men and women were similar in age (P<\/jats:italic> = 0.23). The mean number of baseline comorbidities was higher in women (2.7, 95% confidence interval [CI<\/jats:styled-content>]: 2.5\u20102.9) compared to men (2.3, 95% CI<\/jats:styled-content>: 2.1\u20102.4, P<\/jats:italic> = 0.0002). The risk\u2010adjusted odds ratios (OR<\/jats:styled-content>) of female gender to death at 5 years (OR<\/jats:styled-content>: 1.12, 95% CI<\/jats:styled-content>: 0.83\u20101.52), MI<\/jats:styled-content> (OR<\/jats:styled-content>: 1.19, 95% CI<\/jats:styled-content>: 0.86\u20101.64), and repeat revascularization (OR<\/jats:styled-content>: 1.01, 95% CI<\/jats:styled-content>: 0.70\u20101.45) were similar to men. Age modified the effect of gender for the primary outcome death (P<\/jats:italic>interaction<\/jats:sub>\u2009<\u20090.048), with a trend toward worse outcomes in younger women and improved outcomes in older women. This effect was noted more in patients who underwent coronary artery bypass grafting.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Although the overall relative risk of cardiovascular outcomes after coronary revascularization in ESRD<\/jats:styled-content> was equivalent between men and women, age had a significant interaction with gender on overall mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22306","type":"journal-article","created":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T18:32:53Z","timestamp":1404239573000},"page":"546-551","source":"Crossref","is-referenced-by-count":4,"title":["The Association of Gender to Cardiovascular Outcomes After Coronary Artery Revascularization in Patients With End\u2010Stage Renal Disease"],"prefix":"10.1002","volume":"37","author":[{"given":"Ashok","family":"Krishnaswami","sequence":"first","affiliation":[{"name":"Division of Cardiology Kaiser Permanente San Jose Medical Center San Jose California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara I.","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Nephrology Stanford University Stanford California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James J.","family":"Jang","sequence":"additional","affiliation":[{"name":"Division of Cardiology Kaiser Permanente San Jose Medical Center San Jose California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas K.","family":"Leong","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California Oakland California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan S.","family":"Go","sequence":"additional","affiliation":[{"name":"Division of Research Kaiser Permanente Northern California Oakland California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000155337.50423.C9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31823b5fee"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.09.030"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/108925320400800403"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.21976"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.20000"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2012.07.001"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.179796"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.11.1407"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa070829"},{"key":"e_1_2_5_12_1","first-page":"2503","article-title":"A randomized trial of therapies for type 2 diabetes and coronary artery disease","volume":"360","author":"BARI 2D Study Group","journal-title":"N Engl J Med"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1211585"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.82.5.703"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908610"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041031"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000035248.71165.EB"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.001264"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012060554"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-1353-0"},{"key":"e_1_2_5_21_1","unstructured":"Centers for Disease Control and Prevention. 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