{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T14:22:58Z","timestamp":1780582978468,"version":"3.54.1"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,4,14]],"date-time":"2015-04-14T00:00:00Z","timestamp":1428969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["CDA09027-1"],"award-info":[{"award-number":["CDA09027-1"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"name":"iRhythm Inc."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2015,5]]},"abstract":"ABSTRACT<\/jats:title>Background<\/jats:title>Identification of silent atrial fibrillation (AF<\/jats:styled-content>) could prevent stroke and other sequelae.<\/jats:p><\/jats:sec>Hypothesis<\/jats:title>Screening for AF<\/jats:styled-content> using continuous ambulatory electrocardiographic (ECG<\/jats:styled-content>) monitoring can detect silent AF<\/jats:styled-content> in asymptomatic in patients with known risk factors.<\/jats:p><\/jats:sec>Methods<\/jats:title>We performed a single\u2010center prospective screening study using a wearable patch\u2010based device that provides up to 2 weeks of continuous ambulatory ECG<\/jats:styled-content> monitoring (iRhythm<\/jats:styled-content> Technologies, Inc.). Inclusion criteria were age \u226555 years and \u22652 of the following risk factors: coronary disease, heart failure, hypertension, diabetes, sleep apnea. We excluded patients with prior AF<\/jats:styled-content>, stroke, transient ischemic attack, implantable pacemaker or defibrillator, or with palpitations or syncope in the prior year.<\/jats:p><\/jats:sec>Results<\/jats:title>Out of 75 subjects (all male, age 69 \u00b1 8.0 years; ejection fraction 57% \u00b1 8.7%), AF<\/jats:styled-content> was detected in 4 subjects (5.3%; AF<\/jats:styled-content> burden 28% \u00b1 48%). Atrial tachycardia (AT<\/jats:styled-content>) was present in 67% (\u22654 beats), 44% (\u22658 beats), and 6.7% (\u226560 seconds) of subjects. The combined diagnostic yield of sustained AT<\/jats:styled-content>\/AF<\/jats:styled-content> was 11%. In subjects without sustained AT<\/jats:styled-content>\/AF<\/jats:styled-content>, 11 (16%) had \u226530 supraventricular ectopic complexes per hour.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Outpatient extended ECG<\/jats:styled-content> screening for asymptomatic AF<\/jats:styled-content> is feasible, with AF<\/jats:styled-content> identified in 1 in 20 subjects and sustained AT<\/jats:styled-content>\/AF<\/jats:styled-content> identified in 1 in 9 subjects, respectively. We also found a high prevalence of asymptomatic AT<\/jats:styled-content> and frequent supraventricular ectopic complexes, which may be relevant to development of AF<\/jats:styled-content> or stroke. If confirmed in a larger study, primary screening for AF<\/jats:styled-content> could have a significant impact on public health.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22387","type":"journal-article","created":{"date-parts":[[2015,4,14]],"date-time":"2015-04-14T16:26:26Z","timestamp":1429028786000},"page":"285-292","source":"Crossref","is-referenced-by-count":91,"title":["Feasibility of Extended Ambulatory Electrocardiogram Monitoring to Identify Silent Atrial Fibrillation in High\u2010risk Patients: The Screening Study for Undiagnosed Atrial Fibrillation (STUDY\u2010AF<\/scp>)"],"prefix":"10.1002","volume":"38","author":[{"given":"Mintu P.","family":"Turakhia","sequence":"first","affiliation":[{"name":"Department of Cardiology Veterans Affairs Palo Alto Health Care System Palo Alto California"},{"name":"Department of Medicine, Division of Cardiovascular Medicine Stanford University School of Medicine Stanford 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