{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:56:56Z","timestamp":1792097816004,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T00:00:00Z","timestamp":1450742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2016,1]]},"abstract":"ABSTRACT<\/jats:title>Background<\/jats:title>Angina pectoris (AP<\/jats:styled-content>) is common in coronary artery disease (CAD<\/jats:styled-content>), but whether those with diabetes mellitus (DM<\/jats:styled-content>) experience AP<\/jats:styled-content> as often as those without DM<\/jats:styled-content> is unclear.<\/jats:p><\/jats:sec>Hypothesis<\/jats:title>AP<\/jats:styled-content> prevalence is similar in those with vs without DM<\/jats:styled-content> in a community sample with CAD<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>In adults with CAD<\/jats:styled-content> in the US<\/jats:styled-content> NHANES 2001\u20132010, AP<\/jats:styled-content> was determined by self\u2010report and Rose questionnaire and compared by DM<\/jats:styled-content> status. Physical functioning and medication use were also evaluated.<\/jats:p><\/jats:sec>Results<\/jats:title>Of 1957 adults with CAD<\/jats:styled-content>, 619 (28.2%) had DM<\/jats:styled-content>. Prevalence of AP<\/jats:styled-content> was similar in those with vs without DM<\/jats:styled-content> (48.9% vs 46.3%; P<\/jats:italic> = 0.38). There was a trend toward more severe AP<\/jats:styled-content> in those with glycated hemoglobin \u22657% (50.4%) vs <7% (27.1%; P<\/jats:italic> = 0.09). Adjusted logistic regression showed a similar odds of AP<\/jats:styled-content> (1.06, 95% CI: 0.84\u20101.33) in those with vs without DM<\/jats:styled-content>, although among DM<\/jats:styled-content>, a 2\u2010fold greater odds of AP<\/jats:styled-content> in women vs men. Physical functioning was worse in those with vs without AP<\/jats:styled-content> overall (score of 25.9 vs 24.3; P<\/jats:italic> < 0.001) and further diminished within those with comorbid DM<\/jats:styled-content> (26.7 vs 24.0; P<\/jats:italic> < 0.001). Among those with AP<\/jats:styled-content>, those with vs without DM<\/jats:styled-content> were more likely on \u03b2\u2010blockers, statins, angiotensin\u2010converting enzyme inhibitors, and antiplatelet therapy.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>AP<\/jats:styled-content> in CAD<\/jats:styled-content> patients is similar among those with vs without DM<\/jats:styled-content>, despite greater use of evidence\u2010based therapies in DM<\/jats:styled-content> patients. Greater physical limitations exist in those with vs without AP<\/jats:styled-content>, and further diminish with comorbid DM<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22488","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T15:52:02Z","timestamp":1450799522000},"page":"30-36","source":"Crossref","is-referenced-by-count":16,"title":["Angina in Coronary Artery Disease Patients With and Without Diabetes: US<\/scp> National Health and Nutrition Examination Survey 2001\u20132010"],"prefix":"10.1002","volume":"39","author":[{"given":"Gavin","family":"Hui","sequence":"first","affiliation":[{"name":"Heart Disease Prevention Program, Division of Cardiology University of California Irvine California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Koch","sequence":"additional","affiliation":[{"name":"Medical Affairs Gilead Sciences, Inc. Foster City California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Calara","sequence":"additional","affiliation":[{"name":"Medical Affairs Gilead Sciences, Inc. Foster City California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan D.","family":"Wong","sequence":"additional","affiliation":[{"name":"Heart Disease Prevention Program, Division of Cardiology University of California Irvine California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000140677.20606.0E"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.978247"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487314533622"},{"key":"e_1_2_6_5_1","first-page":"645","article-title":"The diagnosis of ischaemic heart pain and intermittent claudication in field surveys","volume":"27","author":"Rose GA","year":"1962","journal-title":"Bull World Health Organ."},{"key":"e_1_2_6_6_1","first-page":"2009","volume-title":"National Health and Nutrition Examination Survey (NHANES) 2007\u20132008 Laboratory Procedures Manual"},{"key":"e_1_2_6_7_1","volume-title":"National Health and Nutrition Examination Survey Physical Functioning Questionnaire","author":"US Department of Health and Human Services","year":"2013"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.05.064"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-013-0568-z"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/AC.69.3.3027827"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.jacc.2013.01.062","article-title":"BARI 2D Study Group. Sex differences in presentation and outcome among patients with type 2 diabetes and coronary artery disease treated with contemporary medical therapy with or without prompt revascularization: a report from the BARI 2D Trial (Bypass Angioplasty Revascularization Investigation 2 Diabetes)","volume":"61","author":"Tamis\u2010Holland JE","journal-title":"J Am Coll Cardiol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2009.1649"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.113.000779"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00524-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00146-2"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/145.8.762"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.22488","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.22488","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T02:32:33Z","timestamp":1696645953000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.22488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,22]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1002\/clc.22488"],"URL":"https:\/\/doi.org\/10.1002\/clc.22488","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,22]]}}}