{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:15:50Z","timestamp":1780344950872,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T00:00:00Z","timestamp":1450742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"ABSTRACT<\/jats:title>Background<\/jats:title>Today, cardiologists seek to minimize time from symptom onset to interventional treatment for the most favorable results.<\/jats:p><\/jats:sec>Hypothesis<\/jats:title>In the acute coronary syndrome (ACS<\/jats:styled-content>) symptom complex, sweating can differentiate ST<\/jats:styled-content>\u2010segment elevation myocardial infarction (STEMI<\/jats:styled-content>) from non\u2013ST<\/jats:styled-content>\u2010segment elevation ACS<\/jats:styled-content> (NSTE\u2010ACS<\/jats:styled-content>) during early hours of infarction.<\/jats:p><\/jats:sec>Methods<\/jats:title>This single\u2010center, prospective, observational study compared symptoms of STEMI<\/jats:styled-content> and NSTE\u2010ACS<\/jats:styled-content> patients admitted from August 2012 to July 2014.<\/jats:p><\/jats:sec>Results<\/jats:title>Of 12 913 patients, 90.56% met ACS<\/jats:styled-content> criteria. Among these, 22.51% had STEMI<\/jats:styled-content>. Typical angina was the most common symptom (83.82%). On stepwise multiple regression, sweating (odds ratio: 97.06, 95% confidence interval [CI<\/jats:styled-content>]: 82.16\u2010114.14, P<\/jats:italic> < 0.0001) and typical angina (odds ratio: 2.72, 95% CI<\/jats:styled-content>: 2.18\u20103.38, P<\/jats:italic> < 0.001) had significant association with STEMI<\/jats:styled-content>. For diagnosis of STEMI<\/jats:styled-content>, positive likelihood ratio (LR<\/jats:styled-content>) and positive predictive value (PPV<\/jats:styled-content>) were highest for typical angina with sweating (LR<\/jats:styled-content>: 11.17, 95% CI<\/jats:styled-content>: 10.31\u201012.1; PPV<\/jats:styled-content>: 76.09, 95% CI<\/jats:styled-content>: 74.37\u201077.75), followed by sweating with atypical angina (LR<\/jats:styled-content>: 3.6, 95% CI<\/jats:styled-content>: 3.07\u20104.21; PPV<\/jats:styled-content>: 50.61, 95% CI<\/jats:styled-content>: 46.45\u201054.76), typical angina (LR<\/jats:styled-content>: 1.05, 95% CI<\/jats:styled-content>: 1.03\u20101.07; PPV<\/jats:styled-content>: 22.97, 95% CI<\/jats:styled-content>: 22.11\u201023.84), and atypical angina (LR<\/jats:styled-content>: 0.77, 95% CI<\/jats:styled-content>: 0.69\u20100.87; PPV<\/jats:styled-content>: 18.09, 95% CI<\/jats:styled-content>: 16.32\u201019.97). C statistic values of 0.859 for typical angina with sweating and 0.519 for typical angina alone reflected high discriminatory value of sweating for STEMI<\/jats:styled-content> prediction.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Presence of sweating with ACS<\/jats:styled-content> symptoms predicts probability of STEMI<\/jats:styled-content>, even before clinical confirmation. Sweating in association with typical or atypical angina is a much better predictor of STEMI<\/jats:styled-content> than NSTE\u2010ACS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22498","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T16:31:41Z","timestamp":1450801901000},"page":"90-95","source":"Crossref","is-referenced-by-count":13,"title":["Sweating: A Specific Predictor of ST\u2010Segment Elevation Myocardial Infarction Among the Symptoms of Acute Coronary Syndrome: Sweating In Myocardial Infarction (SWIMI) Study Group"],"prefix":"10.1002","volume":"39","author":[{"given":"Rajendra K.","family":"Gokhroo","sequence":"first","affiliation":[{"name":"Department of Cardiology Jawaharlal Nehru Medical College and Hospital Ajmer Rajasthan India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhanwar L.","family":"Ranwa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Jawaharlal Nehru Medical College and Hospital Ajmer Rajasthan India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Kishor","sequence":"additional","affiliation":[{"name":"Department of Cardiology Jawaharlal Nehru Medical College and Hospital Ajmer Rajasthan India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumari","family":"Priti","sequence":"additional","affiliation":[{"name":"Department of Cardiology Jawaharlal Nehru Medical College and Hospital Ajmer Rajasthan India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Ananthraj","sequence":"additional","affiliation":[{"name":"Department of Cardiology Jawaharlal Nehru Medical College and Hospital Ajmer Rajasthan India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Jawaharlal Nehru Medical College and Hospital Ajmer Rajasthan 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