{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:38:22Z","timestamp":1786977502936,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    There is increasing evidence that mental stress can manifest as physical diseases. One such condition is mental stress\u2013induced myocardial ischemia (\n                    <jats:styled-content style=\"fixed-case\">MSIMI<\/jats:styled-content>\n                    ); a silent, transient, myocardial ischemic response to stressful conditions. We propose that the cardiac microvasculature may be an important site for the interplay between mental stress and\n                    <jats:styled-content style=\"fixed-case\">MSIMI<\/jats:styled-content>\n                    . This study is a review of the literature discussing the prevalence and emerging mechanisms underlying\n                    <jats:styled-content style=\"fixed-case\">MSIMI<\/jats:styled-content>\n                    . We identified several aspects underlying\n                    <jats:styled-content style=\"fixed-case\">MSIMI<\/jats:styled-content>\n                    , including psychological, genetic, and physiological causes. Several sources suggested that dysfunctional cardiac microvasculature might be a contributing factor in the development of stress\u2010induced myocardial ischemia. The literature also suggested that although\n                    <jats:styled-content style=\"fixed-case\">MSIMI<\/jats:styled-content>\n                    has distinct features and pathophysiology, its occurrence might indicate an increased future risk of cardiovascular events. We found that dysfunctional cardiac microvasculature may be the key point of interaction between mental stress and transient myocardial ischemia and that the development of\n                    <jats:styled-content style=\"fixed-case\">MSIMI<\/jats:styled-content>\n                    might be a \u201csilent\u201d indicator for future cardiac events.\n                  <\/jats:p>","DOI":"10.1002\/clc.22522","type":"journal-article","created":{"date-parts":[[2016,2,20]],"date-time":"2016-02-20T11:52:28Z","timestamp":1455969148000},"page":"234-239","source":"Crossref","is-referenced-by-count":17,"title":["The Role of the Myocardial Microvasculature in Mental Stress\u2013Induced Myocardial Ischemia"],"prefix":"10.1002","volume":"39","author":[{"given":"Huan","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine Guangdong Provincial Hospital of Chinese Medicine Guangzhou Guangdong People's Republic of 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