{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T09:16:35Z","timestamp":1696670195855},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T00:00:00Z","timestamp":1465862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to provide descriptive statistics on patterns of prasugrel usage in the outpatient setting in France. This retrospective study was conducted to describe treatment patterns for prasugrel in the outpatient setting in France using the Intercontinental Marketing Services (<jats:styled-content style=\"fixed-case\">IMS<\/jats:styled-content>) Disease Analyzer database, which collates electronic medical records updated by a nationally representative database of 1200 French general practitioners (<jats:styled-content style=\"fixed-case\">GPs<\/jats:styled-content>). Anonymous data were collected prospectively at each follow\u2010up visit. The study population consisted of patients with \u22651 prescription for prasugrel in the outpatient setting from its launch date to 3 years post\u2010launch. Patients were followed up from the date of the first prescription for prasugrel recorded in the database until they died, changed <jats:styled-content style=\"fixed-case\">GP<\/jats:styled-content>, or reached the end of the study, whichever came first. In France, the <jats:styled-content style=\"fixed-case\">IMS<\/jats:styled-content> Disease Analyzer included 1052 patients receiving \u22651 prescription of prasugrel from January 2010 until October 2012. Eighty\u2010five percent of the population was male. The mean age was 58 years; 94.3% were age &lt;75 years, and 95.0% weighed \u226560 kg. Of the total, 99.8% of patients were prescribed a daily maintenance dose of 10 mg, and 0.2% had a history of transient ischemic attack\/stroke. Concomitant medications were antiplatelet agents (100%; aspirin, 93.7%), lipid\u2010lowering agents (90.1%), \u03b2\u2010blockers (83.7%), angiotensin\u2010converting enzyme inhibitors (62.2%), and anti\u2010ulcer medications (55.1%). The results reflect good usage of prasugrel by French <jats:styled-content style=\"fixed-case\">GPs<\/jats:styled-content> in the outpatient setting, with excellent implementation of the Prasugrel European Summary Product Characteristics.<\/jats:p>","DOI":"10.1002\/clc.22553","type":"journal-article","created":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T15:50:01Z","timestamp":1465919401000},"page":"378-384","source":"Crossref","is-referenced-by-count":1,"title":["Prasugrel Use in Real Life: A Report From the Outpatient Setting in France"],"prefix":"10.1002","volume":"39","author":[{"given":"Pierre","family":"Sabouret","sequence":"first","affiliation":[{"name":"ACTION Study Group, Heart Institute, Cardiology Department, Piti\u00e9\u2010Salp\u00eatri\u00e8re Hospital Pierre and Marie Curie University  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magali","family":"Taiel\u2010Sartral","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit, Health Outcome, Corporate Affairs Lilly France, Neuilly\u2010sur\u2010Seine  France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Chartier","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit, Health Outcome, Corporate Affairs Lilly France, Neuilly\u2010sur\u2010Seine  France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Akiki","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit, Health Outcome, Corporate Affairs Lilly France, Neuilly\u2010sur\u2010Seine  France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Cuisset","sequence":"additional","affiliation":[{"name":"Cardiology Department, Timone University Hospital, and Department of Medicine Aix\u2010Marseille University  Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,14]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Efient 10 mg [summary of product characteristics]. 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Insights from the FAST\u2010MI 2010 registry. Presented at: ESC Congress 2012; August 25\u201329 2012; Munich Germany. Abstract 1389."},{"key":"e_1_2_7_12_1","unstructured":"BelleL SchieleF PuymiratE et al. In\u2010hospital outcomes of patients treated with clopidogrel or prasugrel for acute myocardial infarction in the real world: results from the FAST\u2010MI 2010 registry. Presented at: ESC Congress 2012; August 25\u201329 2012; Munich Germany. 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