{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:37:32Z","timestamp":1765827452065},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T00:00:00Z","timestamp":1464652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Complementary and alternative medicines (<jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content>) are commonly used in patients with cardiovascular disease. Although there is lack of evidence regarding the benefit of <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> on cardiovascular morbidity and mortality, health\u2010status benefits could justify <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>Adoption of mind\u2010body <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> after acute myocardial infarction (<jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>) is associated with improved health status, though other forms of <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> are not associated with health\u2010status improvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content> from 24 <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> sites were assessed for <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> use (categorized as mind\u2010body, biological, and manipulative therapies) prior to and 1 year after <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>. Among patients who reported not using <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> prior to their <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>, association of initiating <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> on patients' health status at 1 year after <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content> was assessed using Angina Frequency and Quality of Life domains from the Seattle Angina Questionnaire and the Short Form\u201012 Physical and Mental Component scales. Multivariable regression helped examine association between use of different <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> therapies and health status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 1884 patients not using <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> at the time of their <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>, 33% reported initiating \u22651 forms of <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> therapy 1 year following <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>: 62% adopted mind\u2010body therapies, 42% adopted biological therapies, and 15% began using manipulative therapies. In both unadjusted and adjusted analyses, we found no association between different types of <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> use and health\u2010status improvement after <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no association between <jats:styled-content style=\"fixed-case\">CAM<\/jats:styled-content> use and health\u2010status recovery after <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>. Until randomized trials suggest otherwise, these findings underscore the importance of focusing on therapies with proven effectiveness after <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22559","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T12:33:08Z","timestamp":1464697988000},"page":"440-445","source":"Crossref","is-referenced-by-count":3,"title":["The Association Between Complementary and Alternative Medicine and Health Status Following Acute Myocardial Infarction"],"prefix":"10.1002","volume":"39","author":[{"given":"Ali","family":"Shafiq","sequence":"first","affiliation":[{"name":"Cardiovascular Outcomes Research Saint Luke's Mid America Heart Institute  Kansas City Missouri"},{"name":"Department of Cardiology School of Medicine, University of Missouri\u2010Kansas City  Kansas City Missouri"},{"name":"Department of Cardiology Children's Mercy Hospital and Clinics  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Jayaram","sequence":"additional","affiliation":[{"name":"Cardiovascular Outcomes Research Saint Luke's Mid America Heart Institute  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensey L.","family":"Gosch","sequence":"additional","affiliation":[{"name":"Cardiovascular Outcomes Research Saint Luke's Mid America Heart Institute  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Spertus","sequence":"additional","affiliation":[{"name":"Cardiovascular Outcomes Research Saint Luke's Mid America Heart Institute  Kansas City Missouri"},{"name":"Department of Cardiology School of Medicine, University of Missouri\u2010Kansas City  Kansas City Missouri"},{"name":"Department of Cardiology Children's Mercy Hospital and Clinics  Kansas City 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