{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:59:29Z","timestamp":1788919169990,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Paravalvular\n regurgitation (<jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content>) remains one of the drawbacks of transcatheter aortic valve implantation (<jats:styled-content style=\"fixed-case\">TAVI<\/jats:styled-content>). Details of percutaneous closure (<jats:styled-content style=\"fixed-case\">PCC<\/jats:styled-content>) of <jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">TAVI<\/jats:styled-content> remain obscure. We aimed to explore the patient characteristics, procedural details, closure devices used, and outcomes of <jats:styled-content style=\"fixed-case\">PCC<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">TAVI<\/jats:styled-content>. A systematic search of the <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PubMed<\/jats:styled-content> and Embase databases from January 2002 to September 2015 was conducted. Reports considered to include same patient were excluded and only the studies with largest cohorts were included. A total of 14 studies including 58 patients (61 cases) were included in the study. A balloon\u2010expandable (<jats:styled-content style=\"fixed-case\">BE<\/jats:styled-content>) valve was used more frequently compared with a self\u2010expandable (<jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>) valve (72.6% vs 27.4%, respectively). The mean success rate was 86.9% (100% and 77.8%, respectively; <jats:italic>P<\/jats:italic> = 0.097). The median number of closure devices used was 1 (range, 1\u20134) and did not differ between <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">BE<\/jats:styled-content> valves (<jats:italic>P<\/jats:italic> = 0.71). Mean time from index procedure to <jats:styled-content style=\"fixed-case\">PCC<\/jats:styled-content> did not differ between <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">BE<\/jats:styled-content> valves (295 \u00b1 380 days vs 379 \u00b1 353 days; <jats:italic>P<\/jats:italic> = 0.71). Seven patients had history of valve\u2010in\u2010valve and 6 patients had procedural success. Among the patients with available follow\u2010up data (94.8%), there were 15 deaths (27.3%). Percutaneous closure of <jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">TAVI<\/jats:styled-content> had a high success rate in selected patients in both <jats:styled-content style=\"fixed-case\">BE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> valves. The success rate, timing, and number of closure devices were similar between <jats:styled-content style=\"fixed-case\">BE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> valves. However, prognosis remains fairly poor.<\/jats:p>","DOI":"10.1002\/clc.22569","type":"journal-article","created":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T11:27:26Z","timestamp":1468236446000},"page":"608-614","source":"Crossref","is-referenced-by-count":15,"title":["Percutaneous Closure of Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation: A Systematic Review"],"prefix":"10.1002","volume":"39","author":[{"given":"Tomo","family":"Ando","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Mount Sinai Beth Israel Medical Center, Icahn School of Medicine at Mount Sinai  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisato","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Shizuoka Medical Center  Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the ALICE (All\u2010Literature Investigation of Cardiovascular 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