{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:44Z","timestamp":1786977404997,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T00:00:00Z","timestamp":1478476800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Heart, Lung, and Blood Institute of the National Institutes of Health","award":["T32HL110837"],"award-info":[{"award-number":["T32HL110837"]}]},{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Although eliminating angina is a primary goal in treating patients with chronic coronary artery disease (CAD), few contemporary data quantify prevalence and severity of angina across US cardiology practices. The authors hypothesized that angina among outpatients with CAD managed by US cardiologists is low and its prevalence varies by site. Among 25 US outpatient cardiology clinics enrolled in the American College of Cardiology Practice Innovation and Clinical Excellence (PINNACLE) registry, we prospectively recruited a consecutive sample of patients with chronic CAD over a 1\u2010 to 2\u2010week period at each site between April 2013 and July 2015, irrespective of the reason for their appointment. Eligible patients had documented history of CAD (prior acute coronary syndrome, prior coronary revascularization procedure, or diagnosis of stable angina) and \u22651 prior office visit at the practice site. Angina was assessed directly from patients using the Seattle Angina Questionnaire Angina Frequency score. Among 1257 patients from 25 sites, 7.6% (n = 96) reported daily\/weekly, 25.1% (n = 315) monthly, and 67.3% (n = 846) no angina. The proportion of patients with daily\/weekly angina at each site ranged from 2.0% to 24.0%, but just over half (56.3%) were on \u22652 antianginal medications, with wide variability across sites (0%\u2013100%). One\u2010third of outpatients with chronic CAD managed by cardiologists report having angina in the prior month, and 7.6% have frequent symptoms. Among those with frequent angina, just over half were on \u22652 antianginal medications, with wide variability across sites. These findings suggest an opportunity to improve symptom control.<\/jats:p>","DOI":"10.1002\/clc.22628","type":"journal-article","created":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T11:18:18Z","timestamp":1478517498000},"page":"6-10","source":"Crossref","is-referenced-by-count":36,"title":["The prevalence and management of angina among patients with chronic coronary artery disease across\n                    <scp>US<\/scp>\n                    outpatient cardiology practices: insights from the Angina Prevalence and Provider Evaluation of Angina Relief (\n                    <scp>APPEAR<\/scp>\n                    ) study"],"prefix":"10.1002","volume":"40","author":[{"given":"Faraz","family":"Kureshi","sequence":"first","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"},{"name":"University of Missouri\u2013Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Shafiq","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"},{"name":"University of Missouri\u2013Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne V.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"},{"name":"University of Missouri\u2013Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensey","family":"Gosch","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracie","family":"Breeding","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwath S.","family":"Kumar","sequence":"additional","affiliation":[{"name":"University of Missouri\u2013Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip G.","family":"Jones","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Spertus","sequence":"additional","affiliation":[{"name":"Saint Luke's Mid America Heart Institute  Kansas City Missouri"},{"name":"University of Missouri\u2013Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/circ.131.suppl_2.o29"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp042317"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.12.1404"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.190827"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.108.847145"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.110.960468"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.295"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.recesp.2012.03.011"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.22479"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.22510"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1136\/hrt.2006.103119","article-title":"Prognosis of stable angina pectoris: why we need larger population studies with higher endpoint resolution","volume":"93","author":"Timmis AD","year":"2007","journal-title":"Heart."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.02.044"},{"key":"e_1_2_6_14_1","first-page":"996","article-title":"Sendon JL, et al","volume":"26","author":"Daly CA","year":"2005","journal-title":"Euro Heart Survey Investigators. The clinical characteristics and investigations planned in patients with stable angina presenting to cardiologists in Europe: from the Euro Heart Survey of Stable Angina. 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