{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T13:53:06Z","timestamp":1740145986583,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T00:00:00Z","timestamp":1489104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>We evaluated the specific association between a fitness\u2010fatness index (<jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content>) and all\u2010cause mortality among a national sample of <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> adults with coronary artery disease, congestive heart failure, or myocardial infarction. This <jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content> has recently emerged in the literature as a novel index of health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>We hypothesize that FFI will be inversely associated with mortality risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content> was calculated as cardiorespiratory fitness divided by waist\u2010to\u2010height ratio. Data from the 1999\u20132006 National Health and Nutrition Examination Survey were used to identify 1206 participants, ages 20 to 85. Person\u2010months of follow\u2010up were calculated from the date of interview until date of death or censoring on December 31, 2011, whichever came first.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In a Cox proportional hazards model, for every 1\u2010<jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content>\u2010unit increase, participants had a 6% reduced all\u2010cause mortality rate (hazard ratio [<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>]: 0.94, 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>]: 0.91\u20100.97, <jats:italic>P<\/jats:italic> = 0.001; N\u2009=\u20091206). Results were similar among those diagnosed with coronary artery disease (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>: 0.94, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.90\u20100.98, <jats:italic>P<\/jats:italic> = 0.007), congestive heart failure (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>: 0.95, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.91\u20100.99, <jats:italic>P<\/jats:italic> = 0.02), or myocardial infarction (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>: 0.96, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.92\u20100.99, <jats:italic>P<\/jats:italic> = 0.04). When examined in isolation, only fitness (and not fatness) was linked with survival benefits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this national sample, increased <jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content> was associated with reduced risk of all\u2010cause mortality; this association was driven by the beneficial effects of fitness. This underscores the importance of tailored cardiac rehabilitation programs designed to promote fitness, in particular, among cardiac populations.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22679","type":"journal-article","created":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T17:43:11Z","timestamp":1489167791000},"page":"469-473","source":"Crossref","is-referenced-by-count":12,"title":["The protective effects of a novel fitness\u2010fatness index on all\u2010cause mortality among adults with cardiovascular disease"],"prefix":"10.1002","volume":"40","author":[{"given":"Emily","family":"Frith","sequence":"first","affiliation":[{"name":"Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management The University of Mississippi, University  Mississippi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7711-4741","authenticated-orcid":false,"given":"Paul D.","family":"Loprinzi","sequence":"additional","affiliation":[{"name":"Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management The University of Mississippi, University  Mississippi"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21181"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000461"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6458"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60648-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.11.004"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.038422"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.22576"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157703"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1359786810382057"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2009.00653.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40279\u2010016\u20100641\u20107"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2016.06.008"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.03.008"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2015.08.014"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009387"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008483-200005000-00003"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1398533"},{"key":"e_1_2_6_19_1","first-page":"76","article-title":"Brief walking test and cognitive function among congestive heart failure patients: effect modification by duration of congestive heart failure","volume":"6","author":"Loprinzi PD","year":"2015","journal-title":"Int Cardiovasc Forum J."},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a117191"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113804"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2016.01.008"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2014.09.011"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2016.08.007"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.22679","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.22679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:04:47Z","timestamp":1696637087000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.22679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,10]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1002\/clc.22679"],"URL":"https:\/\/doi.org\/10.1002\/clc.22679","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"type":"print","value":"0160-9289"},{"type":"electronic","value":"1932-8737"}],"subject":[],"published":{"date-parts":[[2017,3,10]]}}}