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Participants undergoing clinically indicated stenting of de novo SVG lesions were randomized in a 1:1 ratio to DES or BMS. Randomization was stratified by presence\/absence of diabetes mellitus and the number of target SVG lesions (1 vs \u22652) within each participating site. At sites that did not routinely administer 12\u2010months of dual antiplatelet therapy after SVG stenting participants without acute coronary syndromes received 1\u2009month of open\u2010label clopidogrel, followed by 11\u2009months of clopidogrel for those assigned to DES and 11\u2009months of placebo for those assigned to BMS. The primary endpoint was the 12\u2010month incidence of target\u2010vessel failure (defined as the composite of cardiac death, target\u2010vessel myocardial infarction, or target\u2010vessel revascularization). Secondary endpoints included the incidence of other clinical endpoints and the incremental cost\u2010effectiveness of DES relative to BMS. 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