{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T23:48:33Z","timestamp":1775260113321,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T00:00:00Z","timestamp":1524700800000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Patients undergoing percutaneous mechanical circulatory support (pMCS)\u2010assisted percutaneous coronary intervention (PCI) represent a high\u2010risk group vulnerable to complications and readmissions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>Thirty\u2010day readmissions after pMCS\u2010assisted PCI are common among patients with comorbidities and account for a significant amount of healthcare spending.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergoing PCI and pMCS (Impella, TandemHeart, or intra\u2010aortic balloon pump) for any indication between January 1, 2012, and November 30, 2014, were selected from the Nationwide Readmissions Database. Patients were identified using appropriate ICD\u20109\u2010CM codes. Clinical risk factors and complications were analyzed for association with 30\u2010day readmission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our analysis included 29 247 patients, of which 4535 (15.5%) were readmitted within 30\u2009days. On multivariate analysis, age\u2009\u2265\u200965\u2009years, female sex, hypertension, diabetes, chronic lung disease, heart failure, prior implantable cardioverter\u2010defibrillator, liver disease, end\u2010stage renal disease, and length of stay \u22655\u2009days during index hospitalization were independent predictors of 30\u2010day readmission. Cardiac etiologies accounted for ~60% of readmissions, of which systolic or diastolic heart failure (22%), stable coronary artery disease (11.1%), acute coronary syndromes (8.9%), and nonspecific chest pain (4.0%) were the most common causes. In noncardiac causes, sepsis\/septic shock (4.6%), hypotension\/syncope (3.2%), gastrointestinal bleed (3.1%), and acute kidney injury (2.6%) were among the most common causes of 30\u2010day readmissions. Mean length of stay and cost of readmissions was 4\u2009days and $16 191, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Thirty\u2010day readmissions after pMCS\u2010assisted PCI are common and are predominantly associated with increased burden of comorbidities. Reducing readmissions for common cardiac etiologies could save substantial healthcare costs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.22893","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T15:22:36Z","timestamp":1524756156000},"page":"450-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Etiologies and predictors of 30\u2010day readmissions in patients undergoing percutaneous mechanical circulatory support\u2013assisted percutaneous coronary intervention in the United States: Insights from the Nationwide Readmissions Database"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6405-1606","authenticated-orcid":false,"given":"Chirag","family":"Bavishi","sequence":"first","affiliation":[{"name":"Department of Cardiology Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Lemor","sequence":"additional","affiliation":[{"name":"Department of Cardiology Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vrinda","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Pulmonary, Critical Care and Sleep Division Yale University School of Medicine  New Haven Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurav","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Temple University Hospital, Philadelphia, Pennsylvania Brown University and Providence VAMC  Rhode Providence Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Moreno","sequence":"additional","affiliation":[{"name":"Department of Cardiology Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Lasala","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Washington University School of Medicine  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert D.","family":"Aronow","sequence":"additional","affiliation":[{"name":"Rhode Island Hospital, Brown Medical School  Rhode Providence Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Dawn Abbott","sequence":"additional","affiliation":[{"name":"Rhode Island Hospital, Brown Medical School  Rhode Providence Island"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.569"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.113.000988"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2016.07.002"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.12.119"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.12.005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022061"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90133-8"},{"key":"e_1_2_6_10_1","unstructured":"Centers for Medicare & Medicaid Services US Department of Health and Human Services. 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