{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:10:49Z","timestamp":1763017849945,"version":"3.37.3"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004411","name":"Heart and Stroke Foundation of Canada","doi-asserted-by":"publisher","award":["#G\u201015\u20100009034"],"award-info":[{"award-number":["#G\u201015\u20100009034"]}],"id":[{"id":"10.13039\/100004411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003579","name":"University of Toronto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003579","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004312","name":"Eli Lilly and Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002973","name":"Daiichi-Sankyo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002973","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>While divorced or living alone, patients with stable cardiovascular disease are at increased risk for adverse cardiovascular events. The importance of marital status following a myocardial infarction (MI) is less clear. We hypothesized that marital status may affect cardiovascular outcomes following MI. We analyzed outcomes among patients with MI who underwent percutaneous coronary intervention from the Canadian Observational Antiplatelet Study (COAPT). Marital status was categorized into 3 groups: married\/common\u2010law patients living together; never married; and divorced, separated, or widowed patients. Patients were followed for 15\u2009months and our primary outcome was the occurrence of a major adverse cardiovascular event (MACE), defined as a composite of mortality, repeat acute MI, stroke, or urgent coronary revascularization. Multivariable logistic regression models were performed, with married\/common\u2010law patients living together considered the reference group. Among 2100 patients included in analyses, 1519 (72.3%) were married\/common\u2010law patients living together, 358 (17.1%) were separated\/divorced\/widowed, and 223 (10.6%) patients were never married. Dual antiplatelet therapy use after 15\u2009months was similar across groups (75.4%, 77.8%, and 73.6%, respectively). The risk of MACE after 15\u2009months was similar among married patients living together (12.7%; referent) compared with patients who were never married (13.9%; adjusted odds ratio: 1.09, 95% confidence interval: 0.58\u20132.07,<jats:italic>P<\/jats:italic>\u2009=\u20090.79) and patients separated\/divorced\/widowed (14.3%; adjusted odds ratio: 0.71, 95% confidence interval: 0.40\u20131.25,<jats:italic>P<\/jats:italic>\u2009=\u20090.23). Similarly, the risk of individual endpoints, including mortality, was similar across the 3 groups. Among patients stabilized following an MI, we found no association between marital status and 15\u2010month outcomes.<\/jats:p>","DOI":"10.1002\/clc.22901","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T18:26:00Z","timestamp":1522002360000},"page":"285-292","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Marital status and outcomes after myocardial infarction: Observations from the Canadian Observational Antiplatelet Study (COAPT)"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4603-8560","authenticated-orcid":false,"given":"Olivia R.","family":"Ghosh\u2010Swaby","sequence":"first","affiliation":[{"name":"Cardiovascular Division, Department of Medicine and Women's College Research Institute Women's College Hospital Toronto Ontario"},{"name":"Faculty of Medical Science, Schulich School of Medicine and Dentistry Western University London Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Tan","sequence":"additional","affiliation":[{"name":"Canadian Heart Research Centre Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshay","family":"Bagai","sequence":"additional","affiliation":[{"name":"Terrence Donnelly Heart Center St. Michael's Hospital, University of Toronto Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2063-7485","authenticated-orcid":false,"given":"Andrew T.","family":"Yan","sequence":"additional","affiliation":[{"name":"Terrence Donnelly Heart Center St. Michael's Hospital, University of Toronto Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaun G.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Canadian Heart Research Centre Toronto Ontario"},{"name":"Terrence Donnelly Heart Center St. Michael's Hospital, University of Toronto Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamir R.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Population Health Research Institute, Hamilton General Hospital McMaster University Hamilton Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold N.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Eli Lilly Canada Inc. Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6243-0186","authenticated-orcid":false,"given":"Eric A.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Schulich Heart Program, Sunnybrook Health Sciences Centre University of Toronto Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thao","family":"Huynh","sequence":"additional","affiliation":[{"name":"Department of Medicine, McGill University Health Centre McGill University Montr\u00e9al Qu\u00e9bec"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warren J.","family":"Cantor","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Southlake Regional Health Centre and University of Toronto Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel R.","family":"Le May","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine University of Ottawa Heart Institute Ottawa Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Pierre","family":"D\u00e9ry","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Qu\u00e9bec Heart and Lung Institute Laval Hospital Qu\u00e9bec City Qu\u00e9bec"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Welsh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mazankowski Alberta Heart Institute University of Alberta Hospital, Canadian VIGOUR Centre Edmonton Alberta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7402-9584","authenticated-orcid":false,"given":"Jacob A.","family":"Udell","sequence":"additional","affiliation":[{"name":"Cardiovascular Division, Department of Medicine and Women's College Research Institute Women's College Hospital Toronto Ontario"},{"name":"Peter Munk Cardiac Centre University Health Network Toronto Ontario"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,25]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Canadian Institute for Health Information. 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