{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:22:46Z","timestamp":1790245366544,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T00:00:00Z","timestamp":1528675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p>Women have been reported to suffer from impaired outcome after acute myocardial infarction (AMI). The aim of our study was to determine the impact of sex and age on utilization of inpatient healthcare and outcome in patients with AMI (STEMI and NSTEMI) in a real\u2010life setting. We performed a routine\u2010data\u2010based analysis of 203 106 nationwide inpatients hospitalized with STEMI and NSTEMI, focusing on sex differences regarding risk constellation, treatments, and in\u2010hospital outcome. A logistic regression model was designed to evaluate the use of coronary angiography and interventions and their sex\u2010related impact on mortality (within 30 days). Compared with males, female STEMI patients (25 146, vs 52 965 males) were older and had a higher incidence of diabetes mellitus (27.4% vs 20.6%), heart failure (32.8% vs 26.2%), and chronic kidney disease (19.1% vs 13.5%, respectively; all <jats:italic>P<\/jats:italic> &lt; 0.05), and had higher observed in\u2010hospital mortality (STEMI, 16.9% vs 9.9%; NSTEMI, 11.7% vs 8.7%). Females were less likely to receive coronary angiography in STEMI in the age groups &lt;60 and \u2265 80 years (odds ratio: 0.8, 95% confidence interval: 0.76\u20130.83, <jats:italic>P<\/jats:italic> &lt; 0.05), despite similar mortality risk reduction. Estimated overall in\u2010hospital mortality showed no differences with respect to sex in STEMI for age groups 40 to 79 years. However, females age \u2265 80 years had slightly higher in\u2010hospital mortality after adjustment. The increased observed in\u2010hospital mortality in females was attributed to the impact of more unfavorable risk and age distribution. Coronary angiography was associated with lower in\u2010hospital mortality; particularly, older females were less frequently treated.<\/jats:p>","DOI":"10.1002\/clc.22962","type":"journal-article","created":{"date-parts":[[2018,4,18]],"date-time":"2018-04-18T03:59:13Z","timestamp":1524023953000},"page":"1013-1021","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Nationwide Routine\u2010Data Analysis of Sex Differences in Outcome of Acute Myocardial Infarction"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4409-3179","authenticated-orcid":false,"given":"Eva","family":"Freisinger","sequence":"first","affiliation":[{"name":"Division of Vascular Medicine, Department of Cardiovascular Medicine University Hospital M\u00fcnster  M\u00fcnster 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