{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T22:04:57Z","timestamp":1781129097667,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Henan Medical Science and Technology Research Project","award":["2018020447"],"award-info":[{"award-number":["2018020447"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Paroxysmal atrial fibrillation (AF) frequently occurs in patients with Wolff\u2010Parkinson\u2010White (WPW) syndrome. Although successful ablation of the accessory pathway (AP) eliminates paroxysmal AF in some patients, in other patients it can recur.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>We investigated the clinical utility of advanced interatrial block (IAB) for predicting the risk of AF recurrence in patients with verified paroxysmal AF and WPW syndrome after successful AP ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 103 patients (70 men, 33 women; mean age, 44\u2009\u00b1\u200916\u2009years) with WPW syndrome who had paroxysmal AF. A resting 12\u2010lead electrocardiogram was performed immediately after successful AP ablation to evaluate the presence of advanced IAB, which was defined as a P\u2010wave duration of &gt;120\u2009ms and biphasic [\u00b1] morphology in the inferior leads.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the mean follow\u2010up period of 30.9\u2009\u00b1\u200920.0 months (range, 2\u201071\u2009months), 16 patients (15.5%) developed AF recurrence. Patients with advanced IAB had significantly reduced event\u2010free survival from AF (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Cox regression analysis with adjustment for the left atrial diameter and CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>\u2010VASc score identified advanced IAB (hazard ratio, 9.18; 95% confidence interval [CI], 2.30\u201036.72; <jats:italic>P<\/jats:italic> = .002) and age\u2009&gt;\u200950\u2009years (hazard ratio, 12.64; 95% CI, 1.33\u2010119.75; <jats:italic>P<\/jats:italic> = .027) as independent predictors of AF recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Advanced IAB was an independent predictor of AF recurrence after successful AP ablation in patients with WPW syndrome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23222","type":"journal-article","created":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T04:38:15Z","timestamp":1561610295000},"page":"806-811","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Advanced interatrial block predicts recurrence of atrial fibrillation after accessory pathway ablation in patients with Wolff\u2010Parkinson\u2010White syndrome"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0224-6920","authenticated-orcid":false,"given":"Jin\u2010Tao","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Cardiology, Henan Provincial People's Hospital Henan Provincial People's Hospital of Henan University, Zhengzhou University People's Hospital, Central China Fuwai Hospital  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan\u2010Qing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Henan Provincial People's Hospital Henan Provincial People's Hospital of Henan University, Zhengzhou University People's Hospital, Central China Fuwai Hospital  Zhengzhou 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