{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:37:24Z","timestamp":1789544244003,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T00:00:00Z","timestamp":1573430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The utility of accelerometer\u2010based activity data to identify patients at risk of sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) has not previously been investigated. The aim of the current study was to determine whether physical activity is associated with manifesting spontaneous sustained VT\/VF requiring emergent defibrillation in patients with an ejection fraction of \u226435%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients consecutively prescribed a wearable cardioverter defibrillator (WCD) from April 2015 to May 2018 were included. Shock data and 4\u2009weeks of physical activity data, beginning with the first week of WCD wear, were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on the ROC curve outcome generated from 4057 patients, average daily step count during the first week accurately predicted those patients with sustained VT\/VF compared to those without (shocked (n = 81) vs nonshocked (n = 3976) area under the curve, c\u2010index = 0.71, 95% CI = 0.65\u20100.77, <jats:italic>P<\/jats:italic> &lt;\u2009.001). An average cutoff of 3637 daily steps during week 1 separated the groups. Patients who averaged fewer than 3637 steps per day during the first week of WCD use were 4.3 times more likely to experience a shock than those who walked more than 3637 steps per day (OR = 4.29, 95% CI = 2.58\u20107.15, <jats:italic>P<\/jats:italic> &lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Average daily step counts are lower in WCD patients who manifest spontaneous VT\/VF. Whether these findings represent a causal or correlational relationship, future studies to encourage a minimum daily step count in high\u2010risk patients may impact the incidence of sustained VT\/VF.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23288","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T18:01:28Z","timestamp":1573495288000},"page":"60-65","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Physical activity is reduced prior to ventricular arrhythmias in patients with a wearable cardioverter defibrillator"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3871-6349","authenticated-orcid":false,"given":"Ashley E.","family":"Burch","sequence":"first","affiliation":[{"name":"East Carolina Heart Institute  Greenville North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"D'Souza","sequence":"additional","affiliation":[{"name":"University of Pennsylvania  Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Rod","family":"Gimbel","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Specialists  Bayside Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Rohrer","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Masuda","sequence":"additional","affiliation":[{"name":"ZOLL Medical  Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Sears","sequence":"additional","affiliation":[{"name":"East Carolina University  Greenville North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Scherr","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"e010108","DOI":"10.1161\/JAHA.118.010108","article-title":"Increased physical activity post\u2010myocardial infarction is related to reduced mortality: results from the SWEDEHEART registry","volume":"7","author":"Orjan E","year":"2018","journal-title":"J Am Heart 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