{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:15:18Z","timestamp":1790014518871,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012465","name":"Dalian Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012465","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Catheter ablation (CA) for atrial fibrillation (AF) in heart failure (HF) patients reduced the mortality but may increase complications and raise the safety concern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>CA for AF in HF patients may not increase the complications vs medical treatment, and it may reduce hospitalizations and mortality and improve heart function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three groups of AF patients were included in the study: 120 congestive HF for their first CA (AFHF\u2010CA), 150 congestive HF who were undergoing medical therapy (AFHF\u2010Med), and 150 patients with normal left ventricular (LV) ejection fraction (LVEF) (AF\u2010CA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 30\u2009\u00b1\u20096 months of follow up, 45.8% of patients in the AFHF\u2010CA and 61.3% of patients in the AF\u2010CA groups maintained sinus rhythm (SR) in comparison with 2.7% in AFHF\u2010Med (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). Hospitalization for HF was significantly lower in AFHF\u2010CA than in AFHF\u2010Med groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). Death occurred in 7.5% of patients in the AFHF\u2010CA group, which was lower than 18% in the AFHF\u2010Med group (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). Significant improvements in heart function were shown in the AFHF\u2010CA group compared to the AFHF\u2010Med group, including LVEF (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), LV end\u2010diastolic diameter (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), and New York Heart Association classification (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), as well as the left atrial diameter (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). AFHF\u2010CA patients required additional ablation more often (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). CA had a better prognosis in paroxysmal AF and tachycardia\u2010related diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CA for AF reduced hospitalizations and mortality and improved heart function, vs medical treatment, and was as safe as CA in those with normal heart function.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23314","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T06:44:19Z","timestamp":1575614659000},"page":"305-314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Safety and efficacy of catheter ablation in atrial fibrillation patients with left ventricular dysfunction"],"prefix":"10.1002","volume":"43","author":[{"given":"Songbing","family":"Long","sequence":"first","affiliation":[{"name":"Department of Cardiovascular, The Central Hospital of Shaoyang  Shaoyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutao","family":"Xi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, Texas Heart Institute  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianjun","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, The First Affiliated Hospital of Dalian Medical University  Dalian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, Texas Heart Institute  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, Texas Heart Institute  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanzong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, The First Affiliated Hospital of Dalian Medical University  Dalian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4791-9666","authenticated-orcid":false,"given":"Yunlong","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, The First Affiliated Hospital of Dalian Medical University  Dalian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1359-7307","authenticated-orcid":false,"given":"Xiaomeng","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular, The First Affiliated Hospital of Dalian Medical University  Dalian China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000132470.78896.A8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn217"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000072767.89944.6E"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfp085"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2009.11.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.111.962688"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","unstructured":"WyseDG WaldoAL DiMarcoJP et al;Atrial Fibrillation Follow\u2010up Investigation of Rhythm Management (AFFIRM) Investigators. 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