{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:21:37Z","timestamp":1790788897381,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:00:00Z","timestamp":1578268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Management of cardiac perforation caused by the lead of a cardiac implantable electronic device (CIED) is currently unclear. This study evaluated the outcomes of transvenous lead extraction (TLE) in patients with cardiac perforation caused by a transvenous lead.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>Removal of perforated lead by transvenous approach is safe and effective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of all patients diagnosed with cardiac perforation by a pacing or defibrillator lead in Peking University People's Hospital from January 2008 to January 2019 were reviewed. We included patients who were managed by TLE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 53 patients (30 men; mean age: 67\u2009\u00b1\u200915\u2009years) with lead perforation managed by TLE were included. Most of the perforated leads (94.9%) were pacemaker leads. Forty\u2010three leads (81.1%) were implanted within 1 year. Ten patients with a high risk of hemopericardium underwent percutaneous subxiphoid pericardial puncture prior to TLE. All 53 culprit leads were removed completely without major complications. Simple traction with or without a locking stylet was sufficient in 51 patients (96.2%). Forty\u2010eight patients (90.6%) had a new active\u2010fixation lead reimplanted. No patients showed evidence of new\u2010onset or worsening pericardial effusion during the procedure and hospital stay. During a median follow\u2010up time of 16\u2009months, no recurrence of symptoms associated with lead perforation or CIED\u2010related infection were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In most patients with lead perforation, TLE can be a safe and effective management approach.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23327","type":"journal-article","created":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T10:04:40Z","timestamp":1578305080000},"page":"386-393","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Outcomes of transvenous lead extraction in patients with lead perforation: A single\u2010center experience"],"prefix":"10.1002","volume":"43","author":[{"given":"Xu","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Cardiac Electrophysiology Peking University People's Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Ze","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Peking University People's Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Peking University People's Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Peking University People's Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihong","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Peking University People's Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8253-8490","authenticated-orcid":false,"given":"Xuebin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Peking University People's Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2005.40003.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2000.tb00845.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12472"},{"key":"e_1_2_7_5_1","first-page":"1031","article-title":"Diagnosis and management of iatrogenic cardiac perforation caused by pacemaker and defibrillator leads","volume":"19","author":"Rajkumar CA","year":"2017","journal-title":"Europace"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12431"},{"key":"e_1_2_7_7_1","first-page":"357","article-title":"Delayed perforation of the right ventricle as a complication of permanent cardiac pacing \u2013 is following the guidelines always the right choice? 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