{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T03:19:54Z","timestamp":1783048794995,"version":"3.54.6"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Increased pericardial fat volume (PFV) is associated with coronary atherosclerosis burden independent of body mass index (BMI) in many clinical studies. However, the association of PFV with markers of coronary atherosclerosis has not yet been assessed by dividing the patients according to BMI categories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>To assess the association of PFV measured by multi\u2010detector CT (MDCT) angiography with coronary atherosclerotic markers (coronary artery calcium score [CAC], plaque type, and luminal stenosis) among BMI categories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 496 patients with suspected coronary artery disease who underwent 64\u2010slice MDCT angiography examination were enrolled. Patients divided into obese, overweight, and normal weight groups according to BMI degree.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PFV showed a significant association with CAC, non\u2010calcified coronary plaque, and significant coronary stenosis in obese group. After adjusting for cardiac risk factors, the association of PFV with the non\u2010calcified coronary plaque and significant coronary stenosis persisted. There was a significant association between PFV with CAC and significant coronary stenosis in normal weight group. The association between PFV with CAC and significant coronary stenosis in normal weight was persisted afar adjusting for cardiac risk factors. No significant association was noted between PFV with coronary plaque type in normal weight group. There was no significant independent association between PFV with coronary atherosclerotic markers in overweight group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Increased PFV was associated with advanced stage atherosclerosis in normal weight group, while increased PFV was associated with non\u2010calcified plaque in obese. These results highlight the differential relationship of PFV with coronary atherosclerotic markers among BMI categories.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23396","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T16:45:44Z","timestamp":1591202744000},"page":"993-998","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pericardial fat volume and coronary atherosclerotic markers among <scp>body mass index<\/scp> groups"],"prefix":"10.1002","volume":"43","author":[{"given":"Mohammed Bader","family":"Hassan","sequence":"first","affiliation":[{"name":"Radiology Department Medicine College, Aliraqia University  Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0238-0460","authenticated-orcid":false,"given":"Hussein","family":"Nafakhi","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Medicine College, University of Kufa  Najaf Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulameer A.","family":"Al\u2010Mosawi","sequence":"additional","affiliation":[{"name":"Radiology Department Medicine College, University Of Kufa  Najaf 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