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A majority of patients self\u2010identified as nonwhite, and nearly two\u2010thirds were young (&lt;45\u2009years) or middle\u2010aged (45\u201064\u2009years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Risk factors varied significantly across age groups; with more women and non\u2010Hispanic whites, hypertension, diabetes, dyslipidemia, prior cardiovascular disease, non\u2010sinus rhythm, and collagen vascular disease in the older age group (\u226565\u2009years); and higher body mass index, smoking, cocaine use, human immunodeficiency virus (HIV) infection and family history of heart disease in the young. Younger women had lower summary socioeconomic scores than younger men. Middle\u2010aged women had more obesity and dysmetabolism, while men had more heavy alcohol use. There was greater disease severity with increasing age; with higher cardiac biomarkers, 3\u2010vessel disease, cardiogenic shock, and coronary artery bypass grafting. Older patients had higher rates of death and death or readmission over 4.3 (interquartile range 2.4, 6.0) years of follow\u2010up. Middle\u2010aged women had higher rates of death or any readmission than men, but these differences were not significant after adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings indicate a high burden of risk factors in younger adults with STEMI from an inner\u2010city community. Programs to target sociobehavioral factors in disadvantaged settings, including substance abuse, obesity, and risk of HIV, are necessary to more effectively address health disparities in STEMI and its adverse consequences.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23412","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:20:18Z","timestamp":1595982018000},"page":"1100-1109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Outcomes of <scp>ST\u2010elevation<\/scp> myocardial infarction by age and sex in a <scp>low\u2010income<\/scp> urban community: The Montefiore <scp>STEMI<\/scp> Registry"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7983-5243","authenticated-orcid":false,"given":"Anna E.","family":"Bortnick","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiology Montefiore Medical Center and Albert 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