{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:31:12Z","timestamp":1759336272699,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T00:00:00Z","timestamp":1609977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Little is known about the prevalence and outcomes of readmission to nonindex hospitals after an admission for acute myocardial infarction complicated by cardiogenic shock (AMI\u2010CS). We aimed to determine the rate of nonindex readmissions following AMI\u2010CS and to evaluate its association with clinical factors, hospitalization cost, length of stay (LOS), and in\u2010hospital mortality rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>Nonindex readmission may lead to worse in\u2010hospital outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the data of inpatients with AMI\u2010CS between 2010 and 2017 using the National Readmission Database. The survey analytical methods recommended by the Healthcare Cost and Utilization Project were used for national estimates. Multiple regression models were used to evaluate the predictors of nonindex readmission, and its association with hospitalization cost, LOS, and in\u2010hospital mortality rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 238\u2009349 patients with AMI\u2010CS, 28028 (11.76%) had an unplanned readmission within 30\u2009days. Of these patients, 7423 (26.48%) were readmitted to nonindex hospitals. Compared with index readmission, nonindex readmission was associated with higher hospitalization costs (p\u2009&lt;\u2009.0001), longer LOS (p\u2009&lt;\u2009.0001), and increased in\u2010hospital mortality rates (p = .0016). Patients who had a history of percutaneous coronary intervention, received intubation\/mechanical ventilation, or left against medical advice during the initial admission had greater odds of a nonindex readmission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Over one\u2010fourth of readmissions following AMI\u2010CS were to nonindex hospitals. These admissions were associated with higher hospitalization costs, longer LOS, and higher in\u2010hospital mortality rates. Further studies are needed to evaluate whether a continuity of care plan in the acute hospital setting can improve outcomes after AMI\u2010CS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23526","type":"journal-article","created":{"date-parts":[[2021,1,10]],"date-time":"2021-01-10T20:41:08Z","timestamp":1610311268000},"page":"200-209","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes after readmission at the index or nonindex hospital following acute myocardial infarction complicated by cardiogenic shock"],"prefix":"10.1002","volume":"44","author":[{"given":"Zhen","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Health Statistics Second Military Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Health Statistics Second Military Medical University  Shanghai China"},{"name":"Department of Respiratory and Critical Care Medicine, Jinling Hospital Nanjing University School of Medicine  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingyi","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Health Statistics Second Military Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Fifth Subcenter of Air Force Health Care Center for Special Services Hangzhou  Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daqing","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Medical Management General Hospital of Central Theater Command  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Health Statistics Second Military Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Cardiology Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3552-9153","authenticated-orcid":false,"given":"Yang","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics School of Medical Sciences, \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2338-9501","authenticated-orcid":false,"given":"Jia","family":"He","sequence":"additional","affiliation":[{"name":"Department of Health Statistics Second Military Medical University  Shanghai China"},{"name":"Department of Health Statistics Tongji University School of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2018.12.007"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00215-P"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00879-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.10.006"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.113.000262"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.11.048"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.117.004310"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.008235"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.110.957498"},{"issue":"20","key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"e1844","DOI":"10.1212\/WNL.0000000000008446","article-title":"Readmission to a different hospital following acute stroke is associated with worse outcomes","volume":"93","author":"Stein LK","year":"2019","journal-title":"Neurology"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.01.051"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2014.2071"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26301"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2018.0380"},{"key":"e_1_2_9_16_1","unstructured":"Project HCaU.Overview of the Nationwide Readmissions Database (NRD).https:\/\/www.hcup-us.ahrq.gov\/nrdoverview.jsp. 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