{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:57:22Z","timestamp":1787921842127,"version":"build-2784847793"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The strategy of anesthesia used during ablation of atrial fibrillation (AF) remains controversial. This study aimed to compare sedation with general anesthesia (GA) for catheter ablation of AF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>The presence of AF is associated with an increased risk of stroke and heart failure and decreased quality of life and survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We carried out a retrospective single\u2010centered study with 351 patients undergoing the first ablation procedure for AF under sedation or GA. The main outcome was freedom from recurrence of AF at 1 year. The total time of staying at the ablation laboratory and procedure cost were also calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Freedom from atrial arrhythmia and ablation time did not differ between AF patients under sedation and GA (77.9% vs 79.9% and 42.27\u2009\u00b1\u20099.84\u2009minutes vs 41.51\u2009\u00b1\u20099.27\u2009minutes, respectively), while the total procedure time and cost were lower in patients who underwent sedation than GA (171.39\u2009\u00b1\u200945.09\u2009minutes vs 202.92\u2009\u00b1\u200943.85 and 8.00\u2009\u00b1\u20097.02 CNY vs 8.79\u2009\u00b1\u200911.63 CNY, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>GA is not superior to sedation, in terms of ablation time and freedom from atrial arrhythmia at 1 year, whereas patients with GA had more anesthesia time and procedure cost than sedation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23528","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T20:30:39Z","timestamp":1609273839000},"page":"218-221","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["General anesthesia is not superior to sedation in clinical outcome and cost\u2010effectiveness for ablation of persistent atrial fibrillation"],"prefix":"10.1002","volume":"44","author":[{"given":"Zhengyan","family":"Wang","sequence":"first","affiliation":[{"name":"Cardiology Department The First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihong","family":"Jia","sequence":"additional","affiliation":[{"name":"Cardiology Department The First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0145-8473","authenticated-orcid":false,"given":"Tieying","family":"Shi","sequence":"additional","affiliation":[{"name":"Cardiology Department The First Affiliated Hospital of Dalian Medical University  Dalian Liaoning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changli","family":"Liu","sequence":"additional","affiliation":[{"name":"Cardiology Department The First Affiliated Hospital of Dalian Medical University  Dalian Liaoning 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catheter ablation of atrial fibrillation performed under general anesthesia: results of a unicentric randomized trial","volume":"63","author":"Staskova K","year":"2017","journal-title":"Vnitr Lek"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13669"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-018-1244-z"}],"container-title":["Clinical 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