{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T16:47:27Z","timestamp":1772729247847,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T00:00:00Z","timestamp":1612742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471690"],"award-info":[{"award-number":["81471690"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>A predictive model using left atrial function indexes obtained by real\u2010time three\u2010dimensional echocardiography (RT\u20103DE) and the blood B\u2010type natriuretic peptide (BNP) level was constructed, and its value in predicting recurrence in patients with early persistent atrial fibrillation (AF) after radiofrequency ablation was explored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 228 patients with early persistent AF who were scheduled to receive the first circular pulmonary vein ablation (CPVA) were enrolled. Clinical data of patients were collected: (1) The blood BNP level was measured before radiofrequency ablation; (2) RT\u20103DE was used to obtain the left atrial (LA) time\u2010volume curve; (3) The clinical characteristics, BNP level and LA function parameters were compared, and logistic regression was used to construct a prediction model with combined parameters; (4) The receiver operating characteristic (ROC) curve was used to examine the diagnostic efficacy of the model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>(1) 215 patients with early persistent AF completed CPVA and the follow\u2010up. After 3\u20136 months of follow\u2010up, the patients were divided into sinus rhythm group (160 cases) and recurrence group (55 cases); (2) The recurrence group showed higher minimum LA volume index, diastolic ejection index, and preoperative BNP (all <jats:italic>p<\/jats:italic>\u2009\u2264\u2009.001), while the sinus rhythm group exhibited higher expansion index (PI) and left atrial appendage peak emptying velocity (<jats:italic>p<\/jats:italic>\u2009\u2264\u2009.001); (3) In univariate analysis, BNP level had the best diagnostic performance in predicting the recurrence of AF(AUC = 0.703). We constructed a model based on LA function and BNP level to predict the recurrence of persistent AF after CPVA. This combined model was better than BNP alone in predicting the recurrence of persistent AF after CPVA (AUC: 0.814 vs. 0.703, z = 2.224, <jats:italic>p<\/jats:italic> = .026).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The combined model of LA function and blood BNP level has good predictive value for the recurrence of early persistent AF after CPVA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23557","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T10:46:14Z","timestamp":1612953974000},"page":"407-414","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A predictive model using left atrial function and B\u2010type natriuretic peptide level in predicting the recurrence of early persistent atrial fibrillation after radiofrequency ablation"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4527-7356","authenticated-orcid":false,"given":"Zhenni","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Division of The Third Affiliated Hospital of Soochow University  Chang Zhou City Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Division of The Third Affiliated Hospital of Soochow University  Chang Zhou City Jiangsu Province China"},{"name":"Department of Cardiovascular Division of The First Affiliated Hospital of Soochow University  Su Zhou City Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuxu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Division of Changzhou Hospital Traditional Chinese Medicine  Chang Zhou City Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huannian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Division of Changzhou Cancer Hospital Affiliated to Soochow University  Chang Zhou City Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoliang","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine of The Third Affiliated Hospital of Soochow University  Chang Zhou City Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuetao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine of The Third Affiliated Hospital of Soochow University  Chang Zhou City Jiangsu Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Division of 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