{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:43:04Z","timestamp":1762299784994},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conventional catheter ablation involves prolonged exposure to ionizing radiation, potentially leading to detrimental health effects. Minimal fluoroscopy (MF) represents a safer alternative, which should be explored. Data on the safety and efficacy of this technique are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>Our hypothesis is that MF is of equal efficacy and safety to conventional catheter ablation with the use of fluoroscopy by performing a meta\u2010analysis of both randomized controlled trials (RCTs) and real\u2010world registry studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pubmed and Embase were searched from their inception to July 2020 for RCTs, cohort and observational studies that assessed the outcomes of catheter ablation using a MF technique versus the conventional approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifteen studies involving 3795 patients were included in this meta\u2010analysis. There was a significant reduction in fluoroscopy and procedural time with no difference in acute success (odds ratio [OR]:0.74, 95% CI: 0.50\u20131.10, p\u00a0=\u00a0.14), long\u2010term success (OR:0.92, 95% CI: 0.65\u20131.31, p\u00a0=\u00a0.38), arrhythmia recurrence (OR:1.24, 95% CI: 0.75\u20132.06, p\u00a0=\u00a0.97) or rate of complications. (OR:0.83, 95% CI: 0.46\u20131.48, p\u00a0=\u00a0.65). Additionally sub\u2010group analysis for those undergoing catheter ablation for atrial fibrillation (AF) did not demonstrate a difference in success or complication rates (OR:0.86, 95% CI: 0.30\u20132.42, p\u00a0=\u00a0.77). Multivariate meta\u2010regression did not identify the presence of moderator variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This updated meta\u2010analysis demonstrated an overall reduction in procedural and fluoroscopy time for those undergoing a minimal fluoroscopic approach. There was no significant difference in either acute or chronic success rates or complications between a MF approach and conventional approach for the management of all arrhythmias including those undergoing catheter ablation for AF.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23609","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T06:49:32Z","timestamp":1621234172000},"page":"814-823","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The use of minimal fluoroscopy for cardiac electrophysiology procedures: A meta\u2010analysis and review of the literature"],"prefix":"10.1002","volume":"44","author":[{"given":"Lorraine Lok Wing","family":"Chiang","sequence":"first","affiliation":[{"name":"Li Ka Shing Faculty of Medicine University of Hong Kong  Hong Kong 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Newcastle University  Newcastle UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengqi","family":"Gong","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Ionic\u2010Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tong","family":"Liu","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Ionic\u2010Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangping","family":"Li","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Ionic\u2010Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology Second 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