{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:26:23Z","timestamp":1791811583672,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:00:00Z","timestamp":1640304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Center\u2010based cardiac rehabilitation (CBCR) improves health outcomes but has some limitations. We designed and validated a telerehabilitation system to overcome these barriers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 67 low\u2010risk acute coronary syndrome patients in a randomized controlled trial allocated 1:1 to a 10\u2010month cardiac telerehabilitation (CTR) program or an 8\u2010week CBCR program. Patients underwent ergospirometry, blood tests, anthropometric measurements, IPAQ, PREDIMED, HADS, and EQ\u20105D questionnaires at baseline and 10 months. Data collectors were blinded to the treatment groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The intention\u2010to\u2010treat analysis included 31 patients in the CTR group and 28 patients in the CBCR group. The primary outcome showed increased physical activity according to the IPAQ survey in the CTR group compared to the CBCR group (median increase 1726 METS\u2010min\/week vs. 636, <jats:italic>p<\/jats:italic>\u2009=\u2009.045). Mean VO2max increased 1.62\u2009ml\/(kg\u2009min) (95% confidence interval [CI]: 0.56\u20132.69, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.004) from baseline in the CTR group, and 0.60\u2009mL\/(kg\u2009min) (<jats:italic>p<\/jats:italic>\u2009=\u2009.40) in the CBCR group. Mean apoB\/apoA\u2010I ratio decreased 0.13 (95% CI: \u22120.03 to 0.24, <jats:italic>p<\/jats:italic>\u2009=\u2009.017) in the CTR group, with no significant change in the CBCR group (<jats:italic>p<\/jats:italic>\u2009=\u2009.092). The median non\u2010HDL cholesterol increased by 7.3\u2009mg\/dl (IQR: \u22122.4 to 18.6, <jats:italic>p<\/jats:italic>\u2009=\u2009.021) in the CBCR group, but the increase was not significant in the CTR group (<jats:italic>p<\/jats:italic>\u2009=\u2009.080). Adherence to a Mediterranean diet, psychological distress, and quality of life showed greater improvement in the CTR group than in the CBCR group. Return\u2010to\u2010work time was reduced with the telerehabilitation strategy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This system allows minimal in\u2010hospital training and prolonged follow\u2010up. This strategy showed better results than CBCR.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23757","type":"journal-article","created":{"date-parts":[[2021,12,25]],"date-time":"2021-12-25T06:53:18Z","timestamp":1640415198000},"page":"31-41","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["A randomized controlled clinical trial of cardiac telerehabilitation with a prolonged mobile care monitoring strategy after an acute coronary syndrome"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4340-6620","authenticated-orcid":false,"given":"Ernesto","family":"Dalli Peydr\u00f3","sequence":"first","affiliation":[{"name":"Department of Cardiology Hospital Arnau de Vilanova Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Sanz Sevilla","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation University Hospital Doctor Peset Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda T.","family":"Tuz\u00f3n Segarra","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital Arnau de Vilanova Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Mir\u00f3 Palau","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"S\u00e1nchez Torrijos","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital Arnau de Vilanova Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4249-557X","authenticated-orcid":false,"given":"Juan","family":"Cos\u00edn Sales","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital Arnau de Vilanova Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa575"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz425"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487320913379"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487318825350"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwaa107"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJR.0b013e32833090ef"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2016-000463"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwab106"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.1923"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"e_1_2_12_13_1","unstructured":"Physical 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