{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:08:46Z","timestamp":1789985326731,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T00:00:00Z","timestamp":1662508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Hypothesis<\/jats:title><jats:p>Glycemic variability in one fact that explain the differences in cardiovascular outcomes. The short\u2010term fasting plasma glucose (FPG) variability may have an on major adverse cardiovascular events (MACE) in type 2 diabetes mellitus (T2DM) patients with ST\u2010segment elevation myocardial infarction (STEMI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study retrospectively analyzed T2DM patients who underwent emergent percutaneous coronary intervention (PCI) due to STEMI in Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, between January 2016 and March 2020. All patients underwent at least 5 FPG measurements during the perioperative period. FPG variability score (FPG\u2010VS) was defined as the percentage of the number of FPG variations\u2009&gt;\u20091\u2009mmol\/L between two adjacent FPG measurements. The Cox proportional\u2010hazards model was used to estimate the relationship between FPG\u2010VS and MACE. A validation set was utilized to further evaluate the prognostic value of FPG\u2010VS in a standardized STEMI diabetic diet cohort following PCI intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 612 patients were included in the retrospective cohort study. In comparison to the minimum quintile, FPG\u2010VS\u2009&gt;\u200960% was associated with an increased risk of 30\u2010day MACE. Moreover, compared to FPG\u2010VS\u2009\u2264\u200920%, the FPG\u2010VS\u2009&gt;\u200980% group had a higher risk of MACE (odd ratio [OR]\u2009=\u20094.87, 95% confidence interval [CI]: 2.55\u22125.28), recurrent angina pectoris (OR\u2009=\u20095.43, 95%\u00a0CI: 2.27\u22128.27), nonfatal myocardial infarction (OR\u2009=\u20095.00, 95%\u00a0CI: 2.47\u22127.69), heart failure (OR\u2009=\u20093.70, 95%\u00a0CI: 1.92\u22125.54), malignant arrhythmia (OR\u2009=\u20094.63, 95%\u00a0CI: 1.12\u22126.25) and cardiac death (OR\u2009=\u20091.41, 95%\u00a0CI: 0.17\u22121.97). Consistent results were obtained after adjustment for HbA1c, demonstrating the robustness of FPGFPG\u2010VS. Moreover, the standard diet intervention group had a lower FPG\u2010VS index as well as a lower incidence of MACE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Higher FPG variability is associated with an increased risk of MACE within 30 days in diabetes patients receiving PCI for STEMI. A standardized diet may improve the prognosis of STEMI patients by reducing the FPG\u2010VS.\u00a0<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23899","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T08:09:32Z","timestamp":1662538172000},"page":"1246-1254","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Day\u2010to\u2010day fasting plasma glucose variability on the short\u2010term prognosis of ST\u2010segment elevation myocardial infarction: A retrospective cohort study"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-1651","authenticated-orcid":false,"given":"Ming","family":"Yi","sequence":"first","affiliation":[{"name":"Department of Cardiology Liuyang Hospital of Traditional Chinese Medicine Liuyang China"},{"name":"Department of Clinical Medicine University of South China Hengyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, The Fourth Hospital of Changsha Changsha Hospital Affiliated to Hunan Normal University Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010hui","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat\u2010sen Cardiovascular Hospital) Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine University of South China Hengyang China"},{"name":"Department of Cardiology Shenzhen Traditional Chinese Medicine Hospital Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Ke","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine University of South China Hengyang China"},{"name":"Department of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, (Shenzhen Sun Yat\u2010sen Cardiovascular Hospital) Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.9346"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-1574"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802743"},{"issue":"3","key":"e_1_2_10_5_1","first-page":"6","article-title":"Intensive glucose control increased mortality and did not prevent cardiovascular events in type 2 diabetes","volume":"149","author":"Montori VM","year":"2008","journal-title":"ACP J Club"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(18)30136-0"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-2541"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2020-001753"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154451"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-020-01112-6"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-017-4423-z"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-020-01085-6"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-019-0858-5"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-020-01091-8"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-0823"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005113421910"},{"issue":"1","key":"e_1_2_10_17_1","first-page":"59","article-title":"Predictors and nomogram prediction model of in\u2010stent restenosis within 2 years after drug\u2010eluting stents implantation","volume":"30","author":"Yi M","year":"2022","journal-title":"Chinese J\u00a0Arterioscler"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13565"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-020-01194-2"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11092177"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2020-001557"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.09.025"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.23899","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/clc.23899","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.23899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T16:27:57Z","timestamp":1692462477000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.23899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,7]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/clc.23899"],"URL":"https:\/\/doi.org\/10.1002\/clc.23899","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,7]]},"assertion":[{"value":"2022-03-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}