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VAI was calculated using body mass index (BMI), waist circumference (WC), triglycerides (TG), and high\u2010density lipoprotein cholesterol. VAI was analyzed as a continuous and categorical variable to examine its association with HF. Subgroup analysis was also performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The highest VAI (fourth quartile [Q4]) was found among males, BMI, systolic and diastolic blood pressure, WC, hypertension, diabetes, liver disease, coronary heart disease, smoking, total cholesterol, and TG. More participants in Q4 took \u03b2\u2010receptor blockers, angiotensin\u2010converting enzyme inhibitors\/angiotensin II receptor blockers\/angiotensin receptor\u2010neprilysin inhibitor, calcium channel blockers, and antidiabetic and antihyperlipidemic medications. Participants with HF exhibited greater VAI. A per\u2010unit increase in VAI resulted in a 4% increased risk for HF (odds ratio [OR] 1.04 [95% confidence interval (CI) 1.02\u20131.05]). After multivariable adjustment, compared with the lowest quartile, the OR for Q3 was 1.55 (95% CI 1.24\u20131.94). Subgroup analysis revealed no significant interactions between VAI and specific subgroups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>VAI was independently associated with the risk for HF. As a noninvasive index of visceral adiposity, VAI could be used for a \u201cone shot\u201d assessment of HF risk and may serve as a novel marker.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.23976","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T09:39:25Z","timestamp":1674034765000},"page":"310-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Association between visceral adiposity index and heart failure: A cross\u2010sectional study"],"prefix":"10.1002","volume":"46","author":[{"given":"Xinyu","family":"Zhang","sequence":"first","affiliation":[{"name":"Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of 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