{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T13:52:39Z","timestamp":1740145959534,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T00:00:00Z","timestamp":1681430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with nonischemic dilated cardiomyopathy (DCM)\u00a0are susceptible to arrhythmias and implantable cardioverter defibrillator (ICD)\u00a0in addition to medical treatments may help prevent sudden cardiac death (SCD)\u00a0and improve survival in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>We aim to investigate the impact of ICD insertion on survival and prognosis of patients with nonischemic DCM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed data from patients with nonischemic DCM treated with medical therapy with or without ICD who referred to our hospital from January 2020 to November 2021. Patients were divided based on the treatment that they had received into two equal groups. Different variables including demographic features, comorbidities, medical treatments, hospitalization rate, function class,\u00a0and left ventricular ejection fraction\u00a0before and after treatments were investigated in this study. In addition, variables in survival including overall survival (OS) and\u00a0SCD\u00a0were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 120 patients were investigated in this study. Mean\u2009\u00b1\u2009SD\u00a0of age and follow\u2010up time of patients were 64.0\u2009\u00b1\u200912.7 years old and 61.2\u2009\u00b1\u200915.9 months, respectively. Ten (16.7%) patients with medical therapy, and seven (11.7%) patients with ICD and medical therapy died during the follow\u2010up period (<jats:italic>p<\/jats:italic>\u2009=\u20090.25).\u00a0However, the two groups had a significant difference regarding SCD (11.7% vs. 1.7%, <jats:italic>p<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with nonischemic DCM who had undergone ICD insertion in addition to standard medical treatments, SCD was significantly reduced compared with patients receiving just medical treatments. OS had no significant difference between our two studied groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.24022","type":"journal-article","created":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T07:21:01Z","timestamp":1681456861000},"page":"674-679","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The impact of implantable cardioverter defibrillator on the prognosis of nonischemic dilated cardiomyopathy patients compared with standard medical treatments"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8191-8216","authenticated-orcid":false,"given":"Hossein","family":"Salehi Omran","sequence":"first","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Science Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah","family":"Naghashzadeh","sequence":"additional","affiliation":[{"name":"Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung diseases (NRITLD) Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8849-329X","authenticated-orcid":false,"given":"Rana","family":"Irilouzadian","sequence":"additional","affiliation":[{"name":"Burn Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sina","family":"Dolatshahi","sequence":"additional","affiliation":[{"name":"School of Medicine Shahid Beheshti University of Medical Science Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Taghi","family":"Hedayati Goudarzi","sequence":"additional","affiliation":[{"name":"Cardiology Department, Rohani Hospital, School of Medicine Babol University of Medical Sciences Babol Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Taghi","family":"Salehi Omran","sequence":"additional","affiliation":[{"name":"Department of Cardiology Babol University of Medical Sciences Babol Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12944"},{"issue":"1","key":"e_1_2_9_3_1","first-page":"15","article-title":"Dilated cardiomyopathy: a dynamic disease\u2010clinical course, reverse remodeling and prognostic stratification","volume":"17","author":"Merlo M","year":"2006","journal-title":"G Ital 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