{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:51:08Z","timestamp":1762869068580,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T00:00:00Z","timestamp":1684108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the efficacy and safety of percutaneous closure of ventricular septal rupture (VSR) after acute myocardial infarction (AMI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study included 81 patients who underwent transcatheter closure for postinfarction VSR. We analyzed clinical data from hospitalization and the 30\u2010day follow\u2010up, compared clinical data from the survival and death groups, and explored the best closure time and the safety and efficacy of occlusion. The risk factors for death at 30 days were analyzed by logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>C\u2010reactive protein (CRP), white blood cell counts, N\u2010terminal pro brain natriuretic peptide (NT\u2010ProBNP), and aspartate aminotransferase were higher in the death group than in the survival group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), with a higher rate of application of vasoactive drugs, and a shorter time from AMI to operation (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). At 30 days postocclusion, 19 patients (23.5%) had died. The mortality rate was significantly lower for operation performed 3 weeks after AMI than for operation performed within 3 weeks of AMI (12.5% vs. 48%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Devices were successfully implanted in 76 patients, with 16 (21.1%) operation\u2010related complications and 12 (15.8%) valve injuries. Cardiac function improved significantly (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) at discharge (<jats:italic>N<\/jats:italic>\u2009=\u200966) and 30 days after procedure (<jats:italic>N<\/jats:italic>\u2009=\u200962). Qp\/Qs and pulmonary artery systolic pressure decreased significantly, while aortic systolic pressure increased significantly (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Additionally, EF and LVDd improved (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) after occlusion. Increases in CRP and NT\u2010ProBNP were risk factors for death at 30 days after closure (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Percutaneous VSR closure can be a valuable treatment option for suitable patients with VSR.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.24027","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T05:35:06Z","timestamp":1684215306000},"page":"737-744","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Percutaneous closure of ventricular septal rupture after myocardial infarction: A retrospective study of 81 cases"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0358-9247","authenticated-orcid":false,"given":"Tongfeng","family":"Chen","sequence":"first","affiliation":[{"name":"Henan Key Laboratory of Coronary Heart Disease Control, Heart Center of Henan Provincial People's Hospital, Henan Research Center for Cardiovascular Epidemiology, Central China Fuwai Hospital People's Hospital of Zhengzhou University Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhao","family":"Liu","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Coronary Heart Disease Control, Heart Center of Henan Provincial People's Hospital, Henan Research Center for Cardiovascular Epidemiology, Central China Fuwai Hospital People's Hospital of Zhengzhou University Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Coronary Heart Disease Control, Heart Center of Henan Provincial People's Hospital, Henan Research Center for Cardiovascular Epidemiology, Central China Fuwai Hospital People's Hospital of Zhengzhou University Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zirui","family":"Sun","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Coronary Heart Disease Control, Heart Center of Henan Provincial People's Hospital, Henan Research Center for Cardiovascular Epidemiology, Central China Fuwai Hospital People's Hospital of Zhengzhou University Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Han","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Coronary Heart Disease Control, Heart Center of Henan Provincial People's Hospital, Henan Research Center for Cardiovascular Epidemiology, Central China Fuwai Hospital People's Hospital of Zhengzhou University Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuanyu","family":"Gao","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Coronary Heart Disease Control, Heart Center of Henan Provincial People's Hospital, Henan Research Center for Cardiovascular Epidemiology, Central China Fuwai Hospital People's Hospital of Zhengzhou University Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.04.039"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.2.565"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1317"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn524"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-013-0498-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy462"},{"issue":"02","key":"e_1_2_7_8_1","first-page":"87","article-title":"Interventional treatment of common congenital heart diseases: the common view of Chinese medical experts. Part two\u2014interventional treatment of ventricular septal defect","volume":"20","author":"Committee on Congenital Heart Disease, Internal Medicine Branch of Committee of Cardiovascular Diseases, Chinese Physicians Association","year":"2011","journal-title":"J Interven Radiol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.64.3.545"},{"issue":"20","key":"e_1_2_7_10_1","article-title":"Temporal trends in postinfarction ventricular septal rupture: the CIVIAM Registry[J]","volume":"1885","author":"S\u00e1nchez Vega JD","year":"2020","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2022.12.001"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.112.972711"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25989"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005839"},{"issue":"5","key":"e_1_2_7_15_1","first-page":"423","article-title":"Application of intra\u2010aortic balloon pump in 28 patients with post\u2010myocardial infarction ventricular septal rupture [J]","volume":"36","author":"Chen TF","year":"2020","journal-title":"J Clin Cardiol"},{"issue":"10","key":"e_1_2_7_16_1","first-page":"862","article-title":"Risk factors of cardiac rupture in patients with acute myocardial infarction","volume":"44","author":"Liu ZJ","year":"2016","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.24027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T06:09:24Z","timestamp":1692252564000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.24027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,15]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1002\/clc.24027"],"URL":"https:\/\/doi.org\/10.1002\/clc.24027","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"type":"print","value":"0160-9289"},{"type":"electronic","value":"1932-8737"}],"subject":[],"published":{"date-parts":[[2023,5,15]]},"assertion":[{"value":"2022-04-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}