{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:44:06Z","timestamp":1753868646038,"version":"3.41.2"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T00:00:00Z","timestamp":1708819200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Since 2019, Coronavirus disease\u20102019 (COVID\u201019) has raised unprecedented global health crisis. The incidence and impact of atrial fibrillation (AF) on patients with COVID\u201019 remain unclearly defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective cohort study using ICD\u201010 codes to identify patients with a primary diagnosis of COVID\u201019 with or without AF in National Inpatient Sample Database 2020. We compared the outcome of COVID\u201019 patients with a concurrent diagnosis of AF with those without.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis<\/jats:title><jats:p>AF will adversely affect the prognosis of hospitalized COVID\u201019 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 211\u2009619 patients with a primary diagnosis of COVID\u201019 were identified. Among these patients, 31 923 (15.08%) had a secondary diagnosis of AF. Before propensity score matching, COVID\u2010AF cohort was older (75.8 vs. 62.2\u2010year\u2010old, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and had more men (57.5% vs. 52.0%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). It is associated with more comorbidities, mainly including diabetes mellitus (43.7% vs. 39.9%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), hyperlipidemia (54.6% vs. 39.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), chronic kidney disease (34.5% vs. 17.0%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), coronary artery disease (35.3% vs. 14.4%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), anemia (27.8% vs. 18.6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), and cancer (4.8% vs. 3.4%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). After performing propensity score match, a total of 31\u2009862 patients were matched within each group. COVID\u2010AF cohort had higher inpatient mortality (22.2% vs. 15.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and more complications, mainly including cardiac arrest (3.9% vs. 2.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), cardiogenic shock (0.9% vs. 0.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), hemorrhagic stroke (0.4% vs. 0.3%, <jats:italic>p<\/jats:italic>\u2009=\u2009.025), and ischemic stroke (1.3% vs. 0.7%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). COVID\u2010AF cohort was more costly, with a longer length of stay, and a higher total charge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>AF is common in patients hospitalized for COVID\u201019, and is associated with poorer in\u2010hospital mortality, immediate complications and increased healthcare resource utilization.<\/jats:p><\/jats:sec>","DOI":"10.1002\/clc.24240","type":"journal-article","created":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T13:59:25Z","timestamp":1708869565000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The incidence and impact of atrial fibrillation on hospitalized Coronavirus disease\u20102019 patients"],"prefix":"10.1002","volume":"47","author":[{"given":"Haiming","family":"Niu","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine Zhongshan People's Hospital Zhongshan P.R. 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