{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:07:07Z","timestamp":1756994827422},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T00:00:00Z","timestamp":1383177600000},"content-version":"vor","delay-in-days":12632,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1979,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to determine the natural evolution of different clinical types of \u201cunstable angina\u201d, 167 patients were included in a prospective study. After angiography, 11 (6.5%) were excluded because they had no significant coronary lesions. The remaining 156 were sorted into different groups according to their clinical characteristics and were followed up for a period of 24 months at least. After that follow\u2010up period, mortality and incidence of acute myocardial infarction (AMI) were as follows: angina of recent onset (Class III\u2010IV NYHA): 8.5% (3\/35) and 34.2% (12\/35). Progressive angina: 7.4% (2\/27) and 7.4% (2\/27). Intermediate syndrome: 41.6% (10\/24) and 37.5% (9\/24).<\/jats:p><jats:p>Prinzmetal's angina: 10% (1\/10) and 10% (1\/10). Post acute myocardial infarction angina: 35% (7\/20) and 10% (2\/20). Acute persistent ischemia: 2.5% (1\/40) and 20% (8\/40). Comparison of these figures pointed out significant differences (p &lt; 0.001 for mortality and p &lt; 0.03 for AMI incidence respectively).<\/jats:p><jats:p>We conclude that it is clinically possible to identify different groups within the so\u2010called unstable angina. Such a division not only allows for the creation of more homogeneous groups, but it contributes to a more rational therapeutic approach and also permits identification of high risk prodromes of greater complications, such as myocardial infarction or sudden death.<\/jats:p>","DOI":"10.1002\/clc.4960020205","type":"journal-article","created":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T12:31:40Z","timestamp":1383222700000},"page":"113-120","source":"Crossref","is-referenced-by-count":16,"title":["Clinical spectrum of \u201cUnstable Angina\u201d"],"prefix":"10.1002","volume":"2","author":[{"given":"C. A.","family":"Bertolasi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. E.","family":"Tronge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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