{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:17:06Z","timestamp":1699316226513},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T00:00:00Z","timestamp":1383177600000},"content-version":"vor","delay-in-days":12571,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1979,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A double\u2010blind cross\u2010over study has been performed in 10 patients with an established diagnosis of paroxysmal supraventricular tachycardia to compare the effectiveness of three active agents with placebo. The drugs were administered in random sequence for two\u2010week periods with three\u2010day washout intervals and in standard dose regimes as recommended for prophylaxis by authoritative works on the subject. The results suggest that digoxin is ineffective at the recommended dosage. Procaineamide was effective in controlling some arrhythmias, but disopyramide was the most effective agent studied. All these patients showed a mixture of arrhythmias, and also had a lot of ectopic activity. Arrhythmic activity is erratic and unpredictable, and a larger number of patients would need to be studied for long periods of time to obtain enough data for valid statistical assessment.<\/jats:p>","DOI":"10.1002\/clc.4960020302","type":"journal-article","created":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T12:32:55Z","timestamp":1383222775000},"page":"179-184","source":"Crossref","is-referenced-by-count":1,"title":["A double\u2010blind trial of disopyramide, procaineamide and digoxin in paroxysmal supraventricular tachycardia"],"prefix":"10.1002","volume":"2","author":[{"given":"M. W. Millar","family":"Craig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. B.","family":"Raftery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,31]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4809(78)90014-9"},{"key":"e_1_2_1_3_2","first-page":"54","article-title":"A semi\u2010automatic system for the analysis of 24\u2010hour ECG recordings from ambulant subjects","volume":"9","author":"Cashman PMM","year":"1974","journal-title":"Biomed Eng"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.35.10.1009"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(73)90879-5"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5996.569"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1957.tb36693.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)90148-3"},{"key":"e_1_2_1_9_2","first-page":"86","article-title":"The use of disopyramide in the treatment of arrhythmias in ambulatory patients","volume":"4","author":"Jones MBS","year":"1976","journal-title":"J Int Med Res"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)90431-0"},{"key":"e_1_2_1_11_2","first-page":"8","article-title":"The pharmacology of disopyramide","volume":"4","author":"Nayler WG","year":"1976","journal-title":"J Int Med Res"},{"key":"e_1_2_1_12_2","first-page":"128","article-title":"Long\u2010term recording of the ECG in a normal population","volume":"52","author":"Raftery EB","year":"1976","journal-title":"Postgrad Med J"},{"key":"e_1_2_1_13_2","volume-title":"Clinical heart disease","author":"Oram S.","year":"1971"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1963.tb02014.x"},{"key":"e_1_2_1_15_2","volume-title":"Disease of the heart and circulation","author":"Wood P.","year":"1968"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960020302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960020302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T23:17:10Z","timestamp":1699312630000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960020302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,6]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1979,6]]}},"alternative-id":["10.1002\/clc.4960020302"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960020302","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,6]]}}}