{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T04:18:26Z","timestamp":1697775506321},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T00:00:00Z","timestamp":1233705600000},"content-version":"vor","delay-in-days":9258,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1983,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rocky Mountain spotted fever is a serious infectious disease that continues to occur with increasing incidence in various areas of the United States. A high case\u2010fatality ratio (11%) persists in spite of availability of adequate chemotherapeutic agents, and the cardiac involvement may play an important role in the final outcome of some cases. To assess the effect of the disease on left ventricular function 13 patients underwent Mmode echocardiographic examination on admission to a children's hospital. Increased left ventricular dimension was found in 3 patients and decreased left ventricular shortening fraction in 9. Diminished mean velocity of circumferential fiber shortening and increased left ventricular systolic time interval ratios were found in 8 patients and increased mitral valve E point to ventricular septal separation in 9. One patient died and biventricular dilatation with diffuse myocarditis was seen at autopsy. Repeat echo examination was available in 11 patients at follow\u2010up (mean 5 months). Abnormal E mitral point to ventricular septal separation remained in 4 patients and decreased left ventricular shortening fraction in 2. The long\u2010term prognosis for this group is unknown. Myocardial involvement is frequently present in Rocky Mountain spotted fever; close monitoring and aggressive therapeutic approach are essential if the high case\u2010fatality ratio is to be reduced.<\/jats:p>","DOI":"10.1002\/clc.4960061006","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T13:29:02Z","timestamp":1233754142000},"page":"501-506","source":"Crossref","is-referenced-by-count":3,"title":["Left ventricular dysfunction in rocky mountain spotted fever"],"prefix":"10.1002","volume":"6","author":[{"given":"J.","family":"Marin\u2010Garcia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,4]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(52)90051-3"},{"key":"e_1_2_1_2_1","unstructured":"AshburnLL:The basic lesion in Rocky Mountain spotted fever. InSymposium on the Spotted Fever Group of Rickettsiae Publication 7 WRAIR Government Printing Office 19 (1960)"},{"key":"e_1_2_1_3_1","first-page":"210","article-title":"Rocky Mountain spotted fever with thrombocytopenia and atrial fibrillation. A case report","volume":"57","author":"Atwater JS","year":"1968","journal-title":"J Med Assoc Ga"},{"key":"e_1_2_1_4_1","first-page":"357","article-title":"Myocardial involvement in Rocky Mountain spotted fever","volume":"102","author":"Bradford WD","year":"1978","journal-title":"Arch. Pathol Lab Med"},{"key":"e_1_2_1_5_1","first-page":"1228","article-title":"Rocky Mountain spotted fever in childhood","volume":"131","author":"Bradford WD","year":"1977","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.56.3.457"},{"key":"e_1_2_1_7_1","first-page":"1","article-title":"The pathology of Rocky Mountain spotted fever","volume":"177","author":"Lillie RD","year":"1941","journal-title":"National Institute of Health Bulletin"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992287801700901"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(83)80062-9"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1542\/peds.67.3.358","article-title":"Cardiac manifestations of Rocky Mountain spotted fever","volume":"67","author":"Marin\u2010Garcia J","year":"1981","journal-title":"Pediatrics"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(77)80215-4"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1938.62790150006011a"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.6.1072"},{"key":"e_1_2_1_14_1","first-page":"12","article-title":"Summary. Case of specific notifiable disease","volume":"30","year":"1982","journal-title":"United States Morbid Mortal Week Rep"},{"key":"e_1_2_1_15_1","first-page":"1","article-title":"Studies on Rocky Mountain spotted fever","volume":"41","author":"Wolbach SB","year":"1919","journal-title":"J Med Res"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-53-6-1130"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960061006","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960061006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T21:19:50Z","timestamp":1697750390000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960061006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["10.1002\/clc.4960061006"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960061006","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,10]]}}}