{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:12:28Z","timestamp":1761955948944,"version":"build-2065373602"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,2,5]],"date-time":"2009-02-05T00:00:00Z","timestamp":1233792000000},"content-version":"vor","delay-in-days":8650,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1985,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Patients with mitral valve prolapse (MVP) frequently have chest pain, which may be difficult to differentiate from angina pectoris in coronary artery disease (CAD). We performed resting and exercise ECGs, pulmonary arterial pressure measurements, radionuclide ven\u2010triculography (<jats:sup>99m<\/jats:sup>mtechnetium), and perfusion scintigrams (20lthallium) in 56 patients with angiographically proven MVP and no CAD. Pathological results were obtained in 31% of exercise ECGs, 33% of pulmonary arterial pressure measurements during exercise, 22% of radionuclide ventriculographies, and in 75% of thallium perfusion scintigrams. A significant correlation in pathological results was found only between exercise ECG and both radionuclide ventriculography and pulmonary arterial pressure measurements. Because of the high prevalence of falsepositive perfusion scintigrams in patients with typical or atypical chest pain, the use of exercise 2 T1 imaging as a screening method to separate patients with MVP from those with CAD will not be appropriate. The variability of cardiac abnormalities in our patients with MVP and angiographically normal coronary arteries suggests that the MVP syndrome may represent a variable combination of metabolic, ischemic, or myopathic disorders.<\/jats:p>","DOI":"10.1002\/clc.4960080607","type":"journal-article","created":{"date-parts":[[2009,2,5]],"date-time":"2009-02-05T06:51:50Z","timestamp":1233816710000},"page":"341-347","source":"Crossref","is-referenced-by-count":9,"title":["Mitral valve prolapse in the ventriculogram: Scintigraphic, electrocardiographic, and hemodynamic abnormalities"],"prefix":"10.1002","volume":"8","author":[{"given":"U.","family":"Tebbe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Schicha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Voth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Emrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.\u2010L.","family":"Neuhaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Kreuzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-198212000-00008"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.3.499"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1069250"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810080306"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.54.2.203"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.59.4.619"},{"key":"e_1_2_1_8_1","first-page":"421","volume-title":"Advances in Heart Disease","author":"DeMaria AN","year":"1977"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.54.1.3"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90175-4"},{"key":"e_1_2_1_11_1","first-page":"309","article-title":"Space\/time quantitation of thallium\u2010201 myocardial scintigraphy","volume":"22","author":"Garcia E","year":"1981","journal-title":"J Nucl Med"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(72)90161-0"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(81)90282-4"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.77.1.47"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-0620(73)80026-X"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90093-0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.47.1.27"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-009-6744-1_6"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.53.3.464"},{"key":"e_1_2_1_20_1","first-page":"200","article-title":"Left ventricular function at rest and during treadmill exercise in patients with idiopathic mitral valve prolapse","volume":"3","author":"Markworth P","year":"1981","journal-title":"Angiocardiology"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.57.1.19"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.56.2.311"},{"key":"e_1_2_1_23_1","first-page":"6","article-title":"Exercise induced chest pain, myocardial perfusion and stress electrocardiography in patients with mitral valve prolapse (abstr)","volume":"21","author":"McLaughlin P","year":"1977","journal-title":"Circulation 56"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197707072970103"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(81)90283-6"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.44.6.674"},{"key":"e_1_2_1_27_1","first-page":"217","article-title":"Thallium\u2010201 myocardial imaging during exercise in mitral valve prolapse (abstr)","volume":"55","author":"Padmanabhan V","year":"1977","journal-title":"Circulation"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197605132942004"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90926-8"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.50.2.306"},{"key":"e_1_2_1_31_1","first-page":"207","article-title":"Determination of coronary flow velocities in man by a computer\u2010aided cine\u2010videodensitometric system","volume":"72","author":"Sauer G","year":"1983","journal-title":"Z Kardiol"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(83)90705-6"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(83)90704-4"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(83)90706-8"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.2.287"},{"key":"e_1_2_1_36_1","first-page":"31","article-title":"Results of quantitative myocardial scintigraphy with thallium\u2010201 at rest and after maximum exercise. Critical analysis of predictive value and clinical application","volume":"69","author":"Schicha H","year":"1980","journal-title":"Z Kardiol"},{"key":"e_1_2_1_37_1","first-page":"19","volume-title":"Nuklearmedizin in der kardiologischen Praxis","author":"Schicha H","year":"1983"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(77)90003-0"},{"key":"e_1_2_1_39_1","first-page":"249","article-title":"Sektoranalyse der myokardialen 201\u2010T1 Redistributionskinetik","volume":"11","author":"Standke R","year":"1980","journal-title":"Nucl Compact"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90537-4"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960080607","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960080607","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T17:27:34Z","timestamp":1697822854000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960080607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,6]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1985,6]]}},"alternative-id":["10.1002\/clc.4960080607"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960080607","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"type":"print","value":"0160-9289"},{"type":"electronic","value":"1932-8737"}],"subject":[],"published":{"date-parts":[[1985,6]]}}}