{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T20:43:49Z","timestamp":1698007429591},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,2,5]],"date-time":"2009-02-05T00:00:00Z","timestamp":1233792000000},"content-version":"vor","delay-in-days":7920,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1987,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to differentiate idiopathic dilative cardiomyopathy from ischemic \u00e7ardiomyopathy noninvasively, systolic time intervals (STIs) and early diastolic time intervals were investigated in patients with idiopathic dilative cardiomyopathy (n = 11), patients with ischemic cardiomyopathy (n = 8), and normal controls (n = 17). Minimal left ventricular pressure and pulmonary capillary wedge pressure (PCWP) were also measured to clarify the relationship between early diastolic time intervals and early diastolic hemodynamics. Cardiac function estimated by STIs was markedly depressed both in idiopathic dilative cardiomyopathy and ischemic cardiomyopathy, and there was no difference between the two diseases. In early diastolic time intervals, IIA\u2010O time (the interval from the aortic component of the second heart sound to the O point of apexcardiogram) was significantly prolonged both in idiopathic dilative cardiomyopathy (144\u00b131 (SD); p&lt;0.01) and ischemic cardiomyopathy (153\u00b115; p&lt;0.01) compared to normal controls (126\u00b111). IIA\u2010MVO time (the interval from IIA to the mitral valve opening) in idiopathic dilative cardiomyopathy (49\u00b123) was significantly shorter than that in normal controls (70\u00b18; p&lt;0.05). On the contrary, IIA\u2010MVO time in ischemic cardiomyopathy (126\u00b111) was markedly prolonged compared with normal controls (p&lt;0.01) and idiopathic dilative cardiomyopathy (p&lt;0.01). MVO\u2010O time was significantly prolonged in idiopathic dilative cardiomyopathy (94\u00b118; p&lt;0.01). However, it was conversely shortened in ischemic cardiomyopathy (25\u00b115) compared with normal controls (54\u00b17; p&lt;0.01). Minimal left ventricular pressure in ischemic cardiomyopathy was significantly higher than that in idiopathic dilative cardiomyopathy and normal controls (each p&lt;0.05). PCWP in idiopathic dilative cardiomyopathy was relatively higher than that in ischemic cardiomyopathy. The smaller value of pressure difference between PCWP and minimal left ventricular pressure in ischemic cardiomyopathy might contribute to the shortening of MVO\u2010O time. The different characteristics of early diastolic time intervals in idiopathic dilative cardiomyopathy and ischemic cardiomyopathy are of important diagnostic value in differentiating idiopathic dilative cardiomyopathy from ischemic cardiomyopathy noninvasively.<\/jats:p>","DOI":"10.1002\/clc.4960100602","type":"journal-article","created":{"date-parts":[[2009,2,7]],"date-time":"2009-02-07T03:40:39Z","timestamp":1233978039000},"page":"303-308","source":"Crossref","is-referenced-by-count":2,"title":["Clinical significance of early diastolic time intervals for the differentiation of idiopathic dilative cardiomyopathy from ischemic cardiomyopathy"],"prefix":"10.1002","volume":"10","author":[{"given":"M.","family":"Sekiya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kokubu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,5]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(70)90416-3"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(72)90435-8"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(70)90970-0"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.34.6.545"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(84)80202-7"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(74)90121-0"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.49.6.1153"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.66.4.804"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.34.10.1034"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/000331977502601004"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.47.810"},{"key":"e_1_2_1_13_2","first-page":"301","volume-title":"Noninvasive Cardiology","author":"Weissler AM","year":"1974"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.48.3.204"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.68.1.76"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.47.522"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/13.9.514"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(80)90320-8"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/6.3.263"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108522"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.46.124"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(80)90661-4"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.46.58"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.4.756"},{"key":"e_1_2_1_25_2","first-page":"1287","article-title":"Maximal rate of fall of left ventricular pressure in cardiomyopathy and constrictive pericarditis","volume":"49","author":"Lewis BS","year":"1975","journal-title":"S Afr Med J"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.67.3.521"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960100602","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960100602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T04:33:20Z","timestamp":1697862800000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960100602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,6]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1987,6]]}},"alternative-id":["10.1002\/clc.4960100602"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960100602","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,6]]}}}