{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T08:10:26Z","timestamp":1698048626856},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T00:00:00Z","timestamp":1233705600000},"content-version":"vor","delay-in-days":6793,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The short\u2010term hemodynamic and possible arrhythmogenic effects of intravenous salbutamol at a dose of 30 or 60 m\u0308g\/min were evaluated in 14 patients with severe chronic left ventricular dysfunction using equilibrium radionuclide angiocardiography and electrocardiographic monitoring. Salbutamol infusions at a dose of 30 m\u0308g\/min did not cause significant hemodynamic changes; however, at a dose of 60 m\u0308g\/min there was a significant increase in stroke volume, cardiac output, and left ventricular ejection fraction. Heart rate increased significantly while systemic peripheral resistance decreased significantly. Two patients developed ventricular premature beats and another two supraventricular tachycardia, but none were associated with adverse consequences. Thus, high\u2010dose intravenous salbutamol is effective and safe, and may be used in the acute management of patients with poor left ventricular function.<\/jats:p>","DOI":"10.1002\/clc.4960130708","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T21:27:36Z","timestamp":1233782856000},"page":"468-472","source":"Crossref","is-referenced-by-count":0,"title":["Acute hemodynamic and arrhy thmogenic effects of high\u2010dose intravenous salbutamol in patients with chronic left ventricular dysfunction"],"prefix":"10.1002","volume":"13","author":[{"given":"Z.","family":"Rotstein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Battler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Rath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Perek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Eldar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,4]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5652.287"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1969.tb07975.x"},{"key":"e_1_2_1_4_2","first-page":"16","article-title":"Some observations on the pharmacological effects of salbutamol with particular reference to the cardiovascular system","volume":"47","author":"Nayler WG","year":"1971","journal-title":"Postgrad Med J"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.43.5.523"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.284.6309.73"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)90846-X"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6198.1101"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.39.7.721"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5929.502"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)90583-7"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.3.449"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(85)90648-9"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(79)90323-0"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810060107"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(82)90307-1"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.43.2.206"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.42.1073"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(77)80314-1"},{"key":"e_1_2_1_20_2","first-page":"40","article-title":"Hemodynamic effects of intravenous salbutamol in patients with mitral valve disease; comparison with isoprenaline and atropine","volume":"47","author":"Gibson DG","year":"1970","journal-title":"Postgrad Med J"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-92-6-741"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(83)80141-6"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960130708","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960130708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T15:09:48Z","timestamp":1697987388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960130708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1002\/clc.4960130708"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960130708","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}