{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:50:03Z","timestamp":1791179403665,"version":"4.1.0"},"reference-count":73,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T00:00:00Z","timestamp":1233705600000},"content-version":"vor","delay-in-days":6762,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1990,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Reduced heart rate variability carries an adverse prognosis in patients who have survived an acute myocardial infarction. This article reviews the physiology, technical problems of assessment, and clinical relevance of heart rate variability. The sympathovagal influence and the clinical assessment of heart rate variability are discussed. Methods measuring heart rate variability are classified into four groups, and the advantages and disadvantages of each group are described. Concentration is on risk stratification of postmyocardial infarction patients. The evidence suggests that heart rate variability is the single most important predictor of those patients who are at high risk of sudden death or serious ventricular arrhythmias.<\/jats:p>","DOI":"10.1002\/clc.4960130811","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T15:59:45Z","timestamp":1233763185000},"page":"570-576","source":"Crossref","is-referenced-by-count":231,"title":["Heart rate variability"],"prefix":"10.1002","volume":"13","author":[{"given":"M.","family":"Malik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. J.","family":"Camm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,2,4]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1978.tb131339.x"},{"key":"e_1_2_1_3_2","first-page":"R242","article-title":"Special analysis of heart rate variability of lizard, Gallotia galoti","volume":"254","author":"Gonzalez Gonzalez J","year":"1988","journal-title":"Am J Physiol"},{"key":"e_1_2_1_4_2","first-page":"262","article-title":"Effects of Vipera lebetina (Turanica C.) venom on electrocardiogram of Swiss albino mice by heart rate variability technique","volume":"25","author":"Pal S","year":"1987","journal-title":"Ind J Exp Biol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198709000-00014"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.36.3.251"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/dev.420150604"},{"key":"e_1_2_1_8_2","first-page":"227","article-title":"The circadian rhythm of selected parameters of heart rate variability","volume":"35","author":"Stefikova H","year":"1986","journal-title":"Physiol Bohemoslov"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01790662"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00424472"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/00140137308924479"},{"key":"e_1_2_1_12_2","first-page":"553","article-title":"Relationship of reaction time to deceleration and variability of heart rate in nonretarded and retarded persons","volume":"79","author":"Runcie D","year":"1975","journal-title":"Am J Ment Defic"},{"key":"e_1_2_1_13_2","first-page":"663","article-title":"Spectral analysis of heart rate variability as an indicator of driver fatigue","volume":"25","author":"Egelund N","year":"1982","journal-title":"Ergometrics"},{"key":"e_1_2_1_14_2","first-page":"264","article-title":"Spectral analysis of R\u2010R interval variability in inspiratory breath holding in men at rest and during emotional strain","volume":"29","author":"Stancak A","year":"1987","journal-title":"Act Nerv Super"},{"key":"e_1_2_1_15_2","first-page":"66","article-title":"Heart rhythm variability during work in radio speakers","volume":"22","author":"Bronis M","year":"1980","journal-title":"Act Nerv Super"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0001-6918(72)90008-X"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1152\/jappl.1989.66.4.1886","article-title":"Influence of physical training on heart rate variability and baroreflex circulatory control","volume":"66","author":"Seals DR","year":"1989","journal-title":"J AppI Physiol"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.80.1.146"},{"key":"e_1_2_1_19_2","first-page":"167","article-title":"Analyse automatique du rythme cardiaque foetal par ordinateur","volume":"84","author":"Gevaert\u2010Lenain F","year":"1989","journal-title":"Rev Fr Gynecol Obstet"},{"key":"e_1_2_1_20_2","first-page":"108","article-title":"Adaptive filtering in ECG monitoring of the fetal heart rate","volume":"20","author":"Frank TH","year":"1987","journal-title":"J Electrocardiol"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90621-7"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.55.4.348"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(82)90734-7"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.1986.325789"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.59.2.178"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02073645"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7101(87)90014-6"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)91172-1"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90795-8"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90917-4"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90078-X"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02441642"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.52.4.396"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a059428"},{"key":"e_1_2_1_35_2","unstructured":"CrippsTR MalikM FarrellTG CammAJ:Value of heart rate variability after myocardial infarction: A simplified automatic method.Br Heart J(1990) in press"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7101(89)90012-3"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(89)90390-2"},{"key":"e_1_2_1_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/0376-8716(85)90085-7"},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1989.tb03736.x"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.8.1.64"},{"key":"e_1_2_1_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(86)90272-3"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641968809033900"},{"key":"e_1_2_1_43_2","first-page":"578","article-title":"Analysis of heart rate patterns preceding fetal death","volume":"50","author":"Gaziano EP","year":"1977","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90119-3"},{"key":"e_1_2_1_45_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348947808700217"},{"key":"e_1_2_1_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90906-X"},{"key":"e_1_2_1_47_2","first-page":"28","article-title":"Developmental patters of heart rate and heart rate variability during sleep and waking in normal infants and infants at risk for the sudden infant death syndrome","volume":"5","author":"Harper RM","year":"1982","journal-title":"Sleep"},{"key":"e_1_2_1_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-0736(88)90055-6"},{"key":"e_1_2_1_49_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1988.tb37252.x"},{"key":"e_1_2_1_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(89)90077-7"},{"key":"e_1_2_1_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90990-8"},{"key":"e_1_2_1_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)91208-8"},{"key":"e_1_2_1_53_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198801000-00014"},{"key":"e_1_2_1_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90601-1"},{"key":"e_1_2_1_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1838(88)90094-X"},{"key":"e_1_2_1_56_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.61.3.280"},{"key":"e_1_2_1_57_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.84.2.191"},{"key":"e_1_2_1_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(89)90871-0"},{"key":"e_1_2_1_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/0376-8716(86)90040-2"},{"key":"e_1_2_1_60_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.66.4.748"},{"key":"e_1_2_1_61_2","doi-asserted-by":"crossref","first-page":"11B","DOI":"10.1016\/0002-9149(86)90404-2","article-title":"Clinical and research applications of ambulatory Holler ST\u2010segment and heart rate monitoring","volume":"58","author":"Bala Subramanian V","year":"1986","journal-title":"Am J Cardiol"},{"key":"e_1_2_1_62_2","first-page":"61","article-title":"The variability of ST segment in the early phase of acute myocardial infarction","volume":"623","author":"Thygesen K","year":"1978","journal-title":"Acta Med Scand"},{"key":"e_1_2_1_63_2","first-page":"115","article-title":"Variability of negative T wave in hypertrophic cardiomyopathy: Possible role of beta\u2010adrenergic function","volume":"42","author":"Sugishita Y","year":"1987","journal-title":"Acta Cardiol Brux"},{"key":"e_1_2_1_64_2","first-page":"258","article-title":"Long\u2010term spontaneous variability of left ventricular end\u2010diastolic pressure","volume":"18","author":"Fabian J","year":"1976","journal-title":"Cor Vasa"},{"key":"e_1_2_1_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(82)90086-1"},{"key":"e_1_2_1_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)90030-5"},{"key":"e_1_2_1_67_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365518609083729"},{"key":"e_1_2_1_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(67)90132-9"},{"key":"e_1_2_1_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(89)90089-1"},{"key":"e_1_2_1_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)90308-N"},{"key":"e_1_2_1_71_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.62.3.165"},{"key":"e_1_2_1_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(05)80085-7"},{"key":"e_1_2_1_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90396-7"},{"key":"e_1_2_1_74_2","doi-asserted-by":"crossref","unstructured":"MalikM FarrellT CammAJ:Circadian rhythm of heart rate variability after acute myocardial infarction and its influence on the prognostic value of heart rate variability.Am J Cardiol(1990) in press","DOI":"10.1016\/0002-9149(90)90503-S"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960130811","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960130811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T12:15:19Z","timestamp":1697976919000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960130811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,8]]},"references-count":73,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1990,8]]}},"alternative-id":["10.1002\/clc.4960130811"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960130811","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,8]]}}}