{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T11:28:45Z","timestamp":1748431725198},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T00:00:00Z","timestamp":1233705600000},"content-version":"vor","delay-in-days":6153,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1992,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The incidence of neurological residuals following anatomical correction of transposition of the great arteries (d\u2010TGA) has not been described so far. Clinical examination, EEG recordings, and computed tomography (CT) scans were carried out in a consecutive series of 38 children with d\u2010TGA surviving anatomic corrective surgery. The patients were classified into one of three groups according to the type of operation: 15 patients after two\u2010stage approach (TSA) (Stage 1: pulmonary artery banding + aortopulmonary shunt; Stage 2: anatomic correction); 12 patients with primary anatomic correction within the first 2 weeks of life (early switch, ES); 11 patients with primary anatomic correction later in infancy (later switch, LS). In 26 patients (68%) we found no abnormalities on neurologic examination, CT scan, or EEG. Four patients suffered from spastic hemiplegia, 3 of these had cortical brain damage visible on CT scan, and 3 had focal epilepsy as well. In 2 otherwise clinical normal patients cortical infarction could be seen on a CT scan. Thus, in 5 cases (13% of 38 patients) cerebral infarcts were diagnosed by CT scan. The cortical vascular infarction was seen in 4 patients after TSA and in 1 after LS. In 6 patients we found other neurological abnormalities. Early anatomic correction in patients with d\u2010TGA reduces the risk of cortical vascular infarction.<\/jats:p>","DOI":"10.1002\/clc.4960150410","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T12:11:45Z","timestamp":1233749505000},"page":"275-279","source":"Crossref","is-referenced-by-count":9,"title":["Improved neurological outcome following early anatomical correction of transposition of the great arteries"],"prefix":"10.1002","volume":"15","author":[{"given":"N.","family":"Veelken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Gr\u00e4vinghoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.W.","family":"Keck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.J.","family":"Freitag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,4]]},"reference":[{"key":"e_1_2_1_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.40.2.237"},{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.1.80"},{"key":"e_1_2_1_3_2","first-page":"45","article-title":"Neurologische Ver\u00e4nderungen und cerebrale L\u00e4sionen bei Kindern mit Transposition der grossen Arterieu (TGA)","volume":"129","author":"Keck EW","year":"1981","journal-title":"Monatsschr Kinderheilkd"},{"key":"e_1_2_1_4_2","volume-title":"Report","author":"Jatene AD","year":"1977"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0022-5223(19)35789-7","article-title":"The arterial switch operation: An eight\u2010year experience","volume":"92","author":"Quaegebeur JM","year":"1986","journal-title":"Thorac Cardiovasc Surg"},{"key":"e_1_2_1_6_2","first-page":"48","article-title":"An evaluation of one and two stage anatomic correction of simple transposition of the great arteries (abstr)","volume":"68","author":"Yacoub MH","year":"1983","journal-title":"Circulation"},{"key":"e_1_2_1_7_2","volume-title":"Griffith Entwicklungsskalen (GES) zur Beurteilung der Entwicklung in den ersten beiden Lebensjahren.","author":"Brandt I","year":"1983"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(81)80041-8"},{"key":"e_1_2_1_9_2","first-page":"850","volume-title":"Pediatric Cardiology","author":"Anderson RH","year":"1987"},{"key":"e_1_2_1_10_2","first-page":"384","article-title":"Cerebral lesions in congenital heart disease","volume":"89","author":"Berthrong M","year":"1951","journal-title":"Bull John Hopkins Hosp"},{"key":"e_1_2_1_11_2","first-page":"484","article-title":"Cerebral vascular accidents in cyanotic congenital heart disease","volume":"125","author":"Cotrill CM","year":"1973","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_12_2","unstructured":"KimmE:Cerebrale Komplikationen bei Transposition der grossen Arterieu (d\u2010TGA). Ph.D. dissertation University of Hamburg (1980)"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(73)80142-0"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1973.04160020011003"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1957.02330350049004"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.9.2.192"},{"issue":"1","key":"e_1_2_1_17_2","first-page":"399","volume":"2","author":"Brain damage after open heart surgery","year":"1975","journal-title":"Lancet"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(74)80607-4"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/S0022-5223(19)42169-7","article-title":"Neuropathologic complications of cardiac surgery","volume":"61","author":"Aguilar MJ","year":"1971","journal-title":"J Thorac Cardiovasc Surg"},{"key":"e_1_2_1_20_2","first-page":"60","article-title":"Central nervous system consequences in infants of cardiac surgery using deep hypothermia and circulatory arrest","volume":"49","author":"Brunberg JA","year":"1974","journal-title":"Circulation"},{"key":"e_1_2_1_21_2","first-page":"285","article-title":"Zerebrale Komplikationen nach Herzoperationen","volume":"22","author":"Lehmann HJ","year":"1971","journal-title":"Med Welt"},{"key":"e_1_2_1_22_2","first-page":"2078","article-title":"Zerebrale Funktionsst\u00f6rungen nach Herzoperationen","volume":"38","author":"Weigand KH","year":"1969","journal-title":"Med Welt"},{"key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"3165","DOI":"10.1001\/jama.1984.03350220071035","article-title":"Incidence and prognosis of seizures in infants after cardiac surgery with profound hypothermia and circulatory arrest","volume":"252","author":"Ehyai A","year":"1984","journal-title":"J Am Med Assoc"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198406073102303"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960150410","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960150410","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T12:17:02Z","timestamp":1698149822000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960150410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,4]]}},"alternative-id":["10.1002\/clc.4960150410"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960150410","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,4]]}}}