{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T16:37:32Z","timestamp":1785343052589,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T00:00:00Z","timestamp":1233705600000},"content-version":"vor","delay-in-days":5970,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>While patients with end\u2010stage renal disease treated by intermittent hemodialysis have frequent and progressive valve disease, nothing is known of the prevalence and course of valvular abnormalities in patients treated with continuous ambulatory peritoneal dialysis (CAPD). Therefore, valves of 24 CAPD patients (ages 55\u00b111 years; CAPD duration: 29\u00b128 months) were studied in a prospective echocardiographic and Doppler echocardiographic follow\u2010up analysis over 35 months. Most frequent findings were sclerosis of the aortic annulus (100% at both assessments) and of the anterior mitral valve leaflet (first vs. follow\u2010up assessment: 88 vs. 96%). Sclerosis of the mitral valve annulus (58% vs. 63%), right coronary (54 vs. 63%) and noncoronary (50 vs. 67%) cuspis of the aortic valve and of the posterior mitral valve leaflet (25 vs. 50%) were less frequent but tended to be progressive (p=NS). The moderate form of mitral and aortic valve sclerosis was more frequent than the severe form (p&lt;0.01 each) at both assessments. Patients with progressive valve disease were older (60\u00b19 vs. 50\u00b111 years; p&lt;0.025) and had a higher frequency angina pectoris than those without a progression (5 vs. 0 patients; p&lt;0.05). The number of patients with regular sinus rhythm decreased (from 22 to 16; p&lt;0.03), atrial fibrillation developed in four patients, atrioventricular node rhythm following atrioventricular conduction defect developed in one patient, and atrioventricular conduction defect required implantation of a pacemaker in one patient. It is concluded that valvular sclerosis is frequent and progressive in patients with end\u2010stage renal disease treated with long\u2010term CAPD and is associated with supraventricular arrhythmia.<\/jats:p>","DOI":"10.1002\/clc.4960151012","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T12:46:18Z","timestamp":1233751578000},"page":"745-750","source":"Crossref","is-referenced-by-count":18,"title":["Progression of valvular sclerosis in end\u2010stage renal disease treated by long\u2010term peritoneal dialysis"],"prefix":"10.1002","volume":"15","author":[{"given":"J\u00fcrgen","family":"H\u00fcting","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,2,4]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"217","article-title":"The spectrum of echocardiographic findings in chronic renal failure","volume":"3","author":"Schott CR","year":"1978","journal-title":"Cardiovasc Med"},{"key":"e_1_2_1_3_2","first-page":"133","article-title":"Mitral annulus calcification as a manifestation of secondary hyperparathyroidism in chronic renal failure","volume":"62","author":"Jain M","year":"1980","journal-title":"Circulation"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(81)90163-7"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1069160"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000184472"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90401-2"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1068126"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90315-6"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(84)80082-X"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(83)80087-3"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(88)80237-7"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90938-6"},{"key":"e_1_2_1_14_2","first-page":"702","article-title":"H\u00e4ufigkeitszunahme von Staphylococcus\u2010aureus und Staphylococcus\u2010epidermidis\u2010Septik\u00e4mien bei chronischen Dialysepatienten","volume":"81","author":"Srugies S","year":"1986","journal-title":"Med Klin"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.6.1072"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(89)80014-8"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)91040-X"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)90452-2"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90986-4"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)91364-C"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960151012","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960151012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T10:03:09Z","timestamp":1698141789000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960151012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,10]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1992,10]]}},"alternative-id":["10.1002\/clc.4960151012"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960151012","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,10]]}}}