{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T06:40:20Z","timestamp":1698216020407},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T00:00:00Z","timestamp":1233705600000},"content-version":"vor","delay-in-days":5970,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Cardiology"],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Only a few studies deal with electrocardiographic (ECG) signs of left ventricular hypertrophy (LVH) in patients with primary hyperaldosteronism, although it may be presumed that many factors such as arterial hypertension, hypokalemia, increased blood volume, and decreased activity of the renin\u2010angiotensin system can modify LVH pattern in this entity. For that reason, we evaluated ECG signs of LVH in 55 patients with primary hyperaldosteronism hospitalized in our department from 1971 to 1990. These data were compared with age, serum potassium level, plasma renin activity (PRA) and\u2014in 14 patients\u2014with left ventricular mass, measured echocardiographically.<\/jats:p><jats:p>We found inverse correlation between serum potassium concentration and the Sokolow\u2010Lyon index: S<jats:sub>V1<\/jats:sub> + R<jats:sub>V5\/6<\/jats:sub> (r = \u20130.47, p&lt;0.001). Among 24 patients with only abnormal QRS voltage, without ST\u2010T changes suggestive of LVH, 19 (79.2%) had hypokalemia. In multivariate analysis, potassium concentration was the single independent predictor of an abnormal QRS voltage: \u20130.743, p = 0.01 vs. 0.153 (age), \u20130.337 (PRA) and 0.454 (LV mass).<\/jats:p><jats:p>Our observations suggest that hypokalemia is an important factor influencing an amplitude of QRS complexes and may be responsible for false\u2010positive LVH diagnosis.<\/jats:p>","DOI":"10.1002\/clc.4960151030","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T12:41:59Z","timestamp":1233751319000},"page":"725-727","source":"Crossref","is-referenced-by-count":4,"title":["Influence of serum potassium on the electrocardiographic pattern of left ventricular hypertrophy in primary hyperaldosteronism"],"prefix":"10.1002","volume":"15","author":[{"given":"M.","family":"Maciejewska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Dabrowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,4]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"2","article-title":"Characteristics of regression of left ventricular hypertrophy in secondary hypertensive patients successfully treated with surgical procedure","volume":"2","author":"Hamada M","year":"1989","journal-title":"Am J Hypertens"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.48.994"},{"key":"e_1_2_1_4_2","first-page":"157","article-title":"Regression of electrocardiographic left ventricular hypertrophy following treatment of primary hyperaldosteronism","volume":"2","author":"Pringle SD","year":"1988","journal-title":"J Hum Hypertens"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.9.2_Pt_2.II19"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.6.1072"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(49)90562-1"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(68)90035-5"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.16.5.750"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(86)80207-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(86)80044-4"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.55.3.509"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.67.4.907"},{"key":"e_1_2_1_14_2","first-page":"107","article-title":"Effect of left ventricular hypertrophy on amplitude of the QRS complex in patients with arterial hypertension: The electrocardiographic \u2010 echocardiographic correlations","volume":"26","author":"Dabrowska B","year":"1984","journal-title":"Kard Pol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.4.6.731"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.60.2.386"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(79)90107-8"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.65.1.161"}],"container-title":["Clinical Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fclc.4960151030","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/clc.4960151030","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T10:03:23Z","timestamp":1698141803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/clc.4960151030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,10]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1992,10]]}},"alternative-id":["10.1002\/clc.4960151030"],"URL":"https:\/\/doi.org\/10.1002\/clc.4960151030","archive":["Portico"],"relation":{},"ISSN":["0160-9289","1932-8737"],"issn-type":[{"value":"0160-9289","type":"print"},{"value":"1932-8737","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,10]]}}}